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In the United States, asbestos is considered the major cause of malignant mesothelioma [27] and has been considered "indisputably" [28] associated with the development of mesothelioma. Indeed, the relationship between asbestos and mesothelioma is so strong that many consider mesothelioma a "signal" or "sentinel" tumor.
Amosite and crocidolite are considered the most hazardous asbestos fiber types; [5] however, chrysotile asbestos has also produced tumors in animals and is a recognized cause of asbestosis and malignant mesothelioma in humans, [6] and mesothelioma has been observed in people who were occupationally exposed to chrysotile, family members of the ...
Asbestos (/ æ s ˈ b ɛ s t ə s, æ z-,-t ɒ s / ass-BES-təs, az-, -toss) [1] is a group of naturally occurring, toxic, carcinogenic and fibrous silicate minerals.There are six types, all of which are composed of long and thin fibrous crystals, each fibre (particulate with length substantially greater than width) [2] being composed of many microscopic "fibrils" that can be released into ...
Asbestos-related diseases are disorders of the lung and pleura caused by the inhalation of asbestos fibres. Asbestos-related diseases include non-malignant disorders such as asbestosis (pulmonary fibrosis due to asbestos), diffuse pleural thickening, pleural plaques, pleural effusion, rounded atelectasis and malignancies such as lung cancer and malignant mesothelioma.
Some substances cause cancer primarily through their physical, rather than chemical, effects on cells. [32] A prominent example of this is prolonged exposure to asbestos, naturally occurring mineral fibers which are a major cause of mesothelioma, which is a cancer of the serous membrane, usually the serous membrane surrounding the lungs. [32]
Mesothelioma: (cancer of the mesothelium) is a disease in which cells of the mesothelium become abnormal and divide without control or order. They can invade and damage nearby tissues and organs. Cancer cells can also metastasize (spread) from their original site to other parts of the body. Most cases of mesothelioma begin in the pleura or ...
Interventions in areas where asbestos is present often have to follow stringent procedures. Asbestos is a known carcinogen. [5] It is the primary risk factor for mesothelioma, a cancer of the lining of the lungs. [6] It may cause other lung cancers and respiratory diseases such as asbestosis. [7]
Cell growth refers to an increase in the total mass of a cell, including both cytoplasmic, nuclear and organelle volume. [1] Cell growth occurs when the overall rate of cellular biosynthesis (production of biomolecules or anabolism) is greater than the overall rate of cellular degradation (the destruction of biomolecules via the proteasome, lysosome or autophagy, or catabolism).
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