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A549 has also been employed in viral research and associated protein expression changes as a consequence of viral infection. [10] Although A549 is a cancer cell line, it has also been studied for its response to tuberculosis, specifically the production of chemokines as it is induced by the invading bacteria. [11]
Accordingly, the protein profile changes of human lung cancer cell lines A549 in response to periplocin treatment were investigated using proteomics approaches (2-DE combined with MS/MS) in conjunction with Western blot analysis to verify the changed proteins. [36]
Cordycepin has displayed cytotoxicity against some leukemic cell lines in vitro. [8] [9] [10] Additionally, cordycepin displays an effect in cancers, such as lung, [11] renal, [12] colon, [13] and breast cancer. [14] Cordycepin reduces viable A549 lung cancer cell populations by 50%. [11]
Malignant cells such as T-cell leukemia Jurkat, B-cell lymphoma BJAB, colon cancers HT29/219, SW742, fibrosarcoma L929, breast cancer MCF-7, and A549 (lung carcinoma) exhibit preferential cytotoxicity towards it in comparison to primary cells such T cells, human lung fibroblasts, and peripheral blood mononuclear cells (PBMC).
[24] [25] Several studies on various human cancer cell lines including the A549 cell human lung carcinoma line, [11] multiple esophageal cancer cell lines (TE11, YES2, YES5), [26] and cervical cancer cell lines (HeLa, SiHa, and CaSki) [27] showed increased sensitivity to anti-cancer drugs (adriamycin and cisplatin), when endogenous MDC1 protein ...
Download as PDF; Printable version; In other projects ... move to sidebar hide. A549 may refer to: A549 (cell line), a carcinomic human alveolar basal epithelial cell ...
A) Cultured Lewis lung carcinoma epithelioid mouse cells and four human epithelioid cancer cell lines, A549 lung, PC3 prostate, MCF-7 breast, and HT-29 colon cells, secreted high amounts of succinate into their culture media whereas cultures of non-malignant macrophages isolated from the peritoneal cavity of mice did not secrete detectable ...
[38] [7] Putative inhibitors of CYP2J2 inhibit the growth in culture of several human cancer cell lines that express relatively high levels of CYP2J2 viz., Tca-8113 cells, HeLa uterine cervix cell lines, A549 cells, MDA-MB-435 breast cells, and HepG2 cells but they had no significant inhibitory effects on two cell lines that expressed little or ...