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A549 has also been employed in viral research and associated protein expression changes as a consequence of viral infection. [10] Although A549 is a cancer cell line, it has also been studied for its response to tuberculosis, specifically the production of chemokines as it is induced by the invading bacteria. [11]
Accordingly, the protein profile changes of human lung cancer cell lines A549 in response to periplocin treatment were investigated using proteomics approaches (2-DE combined with MS/MS) in conjunction with Western blot analysis to verify the changed proteins. [36]
[24] [25] Several studies on various human cancer cell lines including the A549 cell human lung carcinoma line, [11] multiple esophageal cancer cell lines (TE11, YES2, YES5), [26] and cervical cancer cell lines (HeLa, SiHa, and CaSki) [27] showed increased sensitivity to anti-cancer drugs (adriamycin and cisplatin), when endogenous MDC1 protein ...
Meanwhile, the overexpression of miR-26a in the A549 human lung cancer cell line dramatically inhibits cell proliferation, blocks G1/S phase transition, induces apoptosis, and inhibits cell metastasis and invasion in vitro. Enhancer of zeste homolog 2 (EZH2) is a potential target of miR-26a. [19] Glioma
To further confirm that endogenous wild-type p53 is really causing the repression of survivin gene expression, the authors induced A549 (human lung cancer cell line with wild-type p53) and T47D (human breast cancer cell line with mutant p53) cells with DNA-damaging agent adriamycin to trigger the physiological p53 apoptotic response in these ...
Malignant cells such as T-cell leukemia Jurkat, B-cell lymphoma BJAB, colon cancers HT29/219, SW742, fibrosarcoma L929, breast cancer MCF-7, and A549 (lung carcinoma) exhibit preferential cytotoxicity towards it in comparison to primary cells such T cells, human lung fibroblasts, and peripheral blood mononuclear cells (PBMC).
Cordycepin has displayed cytotoxicity against some leukemic cell lines in vitro. [8] [9] [10] Additionally, cordycepin displays an effect in cancers, such as lung, [11] renal, [12] colon, [13] and breast cancer. [14] Cordycepin reduces viable A549 lung cancer cell populations by 50%. [11]
Print/export Download as PDF; ... move to sidebar hide. A549 may refer to: A549 (cell line), a carcinomic human alveolar basal epithelial cell; A549 road ...
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