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The chorionic villi are at first small and non-vascular. 13–15 days: trophoblast only [1] Secondary: The villi increase in size and ramify, while the mesoderm grows into them. 16–21 days: trophoblast and mesoderm [1] Tertiary: Branches of the umbilical artery and umbilical vein grow into the mesoderm, and in this way the chorionic villi are ...
Commonly used criteria from Altshuler [2] [3] are: "a minimum of 10 villi, each with 10 or more vascular channels, in 10 or more areas of 3 or more random, non-infarcted placental areas when using a ×10 ocular." The Altshuler criteria are not theoretically rigorous, as they do not define the area. Normal villi have up to five vascular channels ...
The term diffuse is used if more than 30% of distal villi are involved. [citation needed] VUE has 2 prominent distinct patterns. Approximately 50% of the cases only involve the distal villi (mature intermediate and terminal villi) and do not involve the proximal stem villi, the anchoring villi embedded in the basal plate, and the chorionic plate.
On gross pathology, the presence of chorionic villi (left) is diagnostic of products of conception, whereas decidua (right) is not. The diagnosis is based on clinical presentation, quantitative HCG, ultrasound, and pathologic evaluation. A solid, heterogeneous, echogenic mass has a positive predictive value of 80%, but is present in only a ...
Massive perivillous fibrin deposition (MPFD, or MFD) refers to excessive deposition of fibrous tissue around the chorionic villi of the placenta. It causes reduced growth of the foetus, and leads to miscarriage in nearly 1 in 3 pregnancies affected. There are typically no symptoms, and it is rarely detected before birth.
Gynecology, pathology Placental villous immaturity is chorionic villous development that is inappropriate for the gestational age . It is associated with diabetes mellitus [ 1 ] and fetal death near term, i.e. intrauterine demise close to the normal gestational period .
Characteristic feature is the identification of intimately related syncytiotrophoblasts and cytotrophoblasts without formation of definite placental type villi. Since choriocarcinomas include syncytiotrophoblasts (beta-HCG producing cells), they cause elevated blood levels of beta-human chorionic gonadotropin .
Histopathology of acute subchorionic intervillositis, with neutrophils in Langhan’s layer of fibrinoid (by the fetal surface, at the base of a chorionic villus, seen at top right). Placentitis is an inflammation of the placenta. The main forms of placentitis are: Villitis, inflammation of chorionic villi.