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Positive histologic stains that aid in the diagnosis of conditions of or affecting the human integumentary system Stain Cell, material, and/or structure(s) stained Condition(s) in which stain is positive Actin-specific enolase: Infantile digital fibromatosis: AE1/AE3: Squamous cell carcinoma: Alcian blue: Lipoid proteinosis Papular mucinosis ...
Examples of non-keratinized stratified squamous epithelium include some parts of the lining of oral cavity, pharynx, conjunctiva of eye, upper one-third esophagus, rectum, vulva, and vagina. Even non-keratinized surfaces, consisting as they do of keratinocytes, have a minor superficial keratinized layer of varying thickness, depending on the ...
Squamous Cell Carcinoma, right upper cheek; Lesion outlined in blue marker with a dashed line prior to biopsy (Original Post: Shared in Squamous Cell Carcinoma) Squamous Cell Carcinoma, well differentiated, left upper paraspinal back marked for biopsy with adjacent actinic keratosis (Original Post: Shared in Squamous Cell Carcinoma )
Cell nuclei should be crisp, blue to black on color [12] [13] and the chromatin patterns of the nucleus should be well defined. Cell cytoplasm stains blue-green and keratin stains orange in color. [13] [5] Eosin Y stains the superficial epithelial squamous cells, nucleoli, cilia, and red blood cells. [2]
The prognosis varies dramatically, depending on the type and stage at the time of treatment. However, the most common epitheliomas are very easily treated and rarely result in death. [ 2 ] The condition did, however, take the life of Scottish golfer Willie Dunn, Sr. in 1878 at a time when the ailment was likely not fully understood.
[2] [6] SGc share a similar histological presentation to other cutaneous tumors, such as sebaceous adenomas, basal cell carcinomas (BCC), squamous cell carcinomas (SCC), and clear cell tumors. [6] [17] A high level of suspicion is extremely important to prevent treatment delay and increased mortality. [17]
The H&E staining procedure is the principal stain in histology [3] [7] [2] [5] in part because it can be done quickly, [7] is not expensive, and stains tissues in such a way that a considerable amount of microscopic anatomy [9] [10] is revealed, [7] [5] [4] and can be used to diagnose a wide range of histopathologic conditions. [8]
This stratified squamous epithelium is maintained by cell division within the stratum basale, in which differentiating cells slowly displace outwards through the stratum spinosum to the stratum corneum, where cells are continually shed from the surface. [3]