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Raynaud syndrome, also known as Raynaud's phenomenon, is a medical condition in which the spasm of small arteries causes episodes of reduced blood flow to end arterioles. [1] Typically the fingers, and, less commonly, the toes, are involved. [ 1 ]
CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc), is a multisystem connective tissue disorder.The acronym "CREST" refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.
Raynaud’s phenomenon, which causes parts of the body like the fingers and the toes to go cold and numb, likely stems from two genes, a study published Thursday in the journal Nature ...
The coexistence of erythromelalgia and Raynaud's phenomenon is rare, but case studies of patients with both diagnoses have been reported in medical journals. [17] Symptoms may present gradually and incrementally, sometimes taking years to become intense enough for patients to seek medical care. In other cases symptoms emerge full blown with onset.
Most patients (over 80%) have vascular symptoms and Raynaud's phenomenon, which leads to attacks of discoloration of the hands and feet in response to cold. Raynaud's normally affects the fingers and toes. Systemic scleroderma and Raynaud's can cause painful ulcers on the fingers or toes, which are known as digital ulcers.
Other uncommon causes are coarctation of the aorta, [4] Trousseau disease [medical citation needed] and Buerger's disease (thromboangiitis obliterans), [5] in which vasculitis occurs. Raynaud's phenomenon functional vasospasm. [clarification needed] It is distinct from neurogenic claudication, which is associated with lumbar spinal stenosis. It ...
For example, when cytotoxic edema occurs in the endothelial cells of the blood–brain barrier, oncotic cell death contributes to loss of integrity of the blood–brain barrier and promotes the progression to vasogenic edema. [8] When brain edema types are combined, there is typically a primary form and the edema type and context of the cause ...
Vasospasm refers to a condition in which an arterial spasm leads to vasoconstriction.This can lead to tissue ischemia (insufficient blood flow) and tissue death ().. Along with physical resistance, vasospasm is a main cause of ischemia.