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  2. Homeobox - Wikipedia

    en.wikipedia.org/wiki/Homeobox

    Most Pax genes contain a homeobox and a paired domain that also binds DNA to increase binding specificity, though some Pax genes have lost all or part of the homeobox sequence. [46] Pax genes function in embryo segmentation , nervous system development, generation of the frontal eye fields , skeletal development, and formation of face structures.

  3. Homeobox protein Nkx-2.5 - Wikipedia

    en.wikipedia.org/wiki/Homeobox_protein_Nkx-2.5

    NK-2 homeobox genes are a family of genes that encode for numerous transcription factors that go on to aid in the development of many structures including the thyroid, colon, and heart. [ 9 ] [ 10 ] [ 11 ] Of the NK-2 genes, NKX2-5 transcription factor is mostly involved in cardiac development and defects with this gene can lead to congenital ...

  4. List of protein subcellular localization prediction tools

    en.wikipedia.org/wiki/List_of_protein_sub...

    It can be applied to any model organism. Currently has 3 modules: a sequence conservation explorer that includes homology relationships and single nucleotide polymorphism data, a protein structure model explorer, a molecular interaction network explorer, a gene product subcellular localization explorer, and a gene expression pattern explorer.

  5. Homeobox protein CDX-2 - Wikipedia

    en.wikipedia.org/wiki/Homeobox_protein_CDX-2

    Homeobox protein CDX-2 is a protein that in humans is encoded by the CDX2 gene. The CDX-2 protein is a homeobox transcription factor expressed in the nuclei of intestinal epithelial cells, [5] [6] playing an essential role in the development and function of the digestive system. CDX2 is part of the ParaHox gene cluster, a group of three highly ...

  6. Homeobox A10 - Wikipedia

    en.wikipedia.org/wiki/Homeobox_A10

    3206 15395 Ensembl ENSG00000253293 ENSMUSG00000000938 UniProt P31260 P31310 RefSeq (mRNA) NM_018951 NM_153715 NM_001122950 NM_008263 RefSeq (protein) NP_061824 NP_001116422 NP_032289 Location (UCSC) Chr 7: 27.17 – 27.18 Mb Chr 6: 52.21 – 52.22 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-A10 is a protein that in humans is encoded by the HOXA10 gene ...

  7. Msh homeobox 2 - Wikipedia

    en.wikipedia.org/wiki/Msh_homeobox_2

    Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. [6] Msx2 is a homeobox gene localized on human chromosome 5 that encodes a transcription repressor and activator (MSX-2) responsible for craniofacial and limb-bud development. Cells will express msx2 when exposed to signaling molecules BMP-2 and BMP-4 in ...

  8. Homeobox protein CDX-1 - Wikipedia

    en.wikipedia.org/wiki/Homeobox_protein_CDX-1

    Homeobox protein CDX-1 is a protein in humans that is encoded by the CDX1 gene. [5] [6] CDX-1 is expressed in the developing endoderm and its expression persists in the intestine throughout adulthood. [7] CDX-1 protein expression varies along the intestine, with high expression in intestinal crypts and diminishing expression along intestinal ...

  9. Homeobox protein goosecoid - Wikipedia

    en.wikipedia.org/wiki/Homeobox_protein_goosecoid

    Homeobox protein goosecoid (GSC) is a homeobox protein that is encoded in humans by the GSC gene. Like other homeobox proteins, goosecoid functions as a transcription factor involved in morphogenesis. In Xenopus, GSC is thought to play a crucial role in the phenomenon of the Spemann-Mangold organizer. [5]