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  2. Gamma-butyrobetaine dioxygenase - Wikipedia

    en.wikipedia.org/wiki/Gamma-butyrobetaine_di...

    Gamma-butyrobetaine dioxygenase (also known as BBOX, GBBH or γ-butyrobetaine hydroxylase) is an enzyme that in humans is encoded by the BBOX1 gene. [5] [6] Gamma-butyrobetaine dioxygenase catalyses the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthesis pathway. [7]

  3. Carnitine - Wikipedia

    en.wikipedia.org/wiki/Carnitine

    L-Carnitine, acetyl-l-carnitine, and propionyl-l-carnitine are available in dietary supplement pills or powders, with a daily amount of 0.5 to 1 g considered to be safe. [1] [3] It is also a drug approved by the Food and Drug Administration to treat primary and certain secondary carnitine-deficiency syndromes secondary to inherited diseases. [1 ...

  4. Carnitine biosynthesis - Wikipedia

    en.wikipedia.org/wiki/Carnitine_biosynthesis

    The second step of L-carnitine biosynthesis requires the 3-hydroxy-N ε-trimethyllysine aldolase enzyme. 3-hydroxy-N ε-trimethyllysine aldolase is a pyridoxal phosphate dependent aldolase, and it catalyses the cleavage of 3-hydroxy-N ε-trimethyllysine into 4-N-trimethylaminobutyraldehyde and glycine.

  5. Nephrotoxicity - Wikipedia

    en.wikipedia.org/wiki/Nephrotoxicity

    Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. [1] There are various forms, [2] and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity.

  6. The #1 Worst Food for Your Kidneys, According to ... - AOL

    www.aol.com/lifestyle/1-worst-food-kidneys...

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  7. Glycine propionyl-L-carnitine - Wikipedia

    en.wikipedia.org/wiki/Glycine_propionyl-l-carnitine

    Results indicated that power output was up to 15% higher following the glycine propionyl-l-carnitine trials compared to placebo, while post-exercise blood lactic acid was 15-16% lower compared to placebo. These data are in reference to trained men performing repeated cycle sprints.

  8. The Common Habit That Could Be Damaging Your Kidneys ... - AOL

    www.aol.com/common-habit-could-damaging-kidneys...

    Dr. Perumal explains that what’s tricky about kidney health is that it’s hard to know that they’re being damaged until they’re in pretty bad shape. “Kidney disease is a silent killer, so ...

  9. Systemic primary carnitine deficiency - Wikipedia

    en.wikipedia.org/wiki/Systemic_primary_carnitine...

    The presentation of patient with SPCD can be incredibly varied, from asymptomatic to lethal cardiac manifestations. [5] Early cases were reported with liver dysfunction, muscular findings (weakness and underdevelopment), hypoketotic hypoglycemia, cardiomegaly, cardiomyopathy and marked carnitine deficiency in plasma and tissues, combined with increased excretion in urine. [5]

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