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Spironolactone can also have numerous other interactions, most commonly with other cardiac and blood pressure medications, for instance digoxin. [8] Licorice, which has indirect mineralocorticoid activity by inhibiting mineralocorticoid metabolism, has been found to inhibit the antimineralocorticoid effects of spironolactone.
Aldosterone receptor antagonists, also known as mineralocorticoid receptor antagonist (MRA) can lower blood pressure by blocking the binding of aldosterone to the mineralocorticoid receptor. Spironolactone and eplerenone are MRAs that causes a block in the reabsorption of sodium, resulting in a decrease in blood pressure. [45] [46] eplerenone
They decrease sodium reabsorption, which leads to increased water excretion by the kidneys. [2] By regulating water excretion, mineralocorticoid receptor antagonists lower blood pressure and reduce fluid around the heart which can be very beneficial in some cardiovascular conditions . [ 3 ]
9 Tips to Lower Blood Pressure. If you have high blood pressure, your first instinct might be to ask about blood pressure medications. While these drugs can help, there are also natural ways to ...
A 2021 study found that yogurt could help reduce blood pressure due to its high concentration of micronutrients calcium, magnesium and potassium, which are all associated with a lower risk of ...
A 2020 study found that high alcohol consumption negatively affected blood pressure and heart rate, while research from 2018 indicated that exercise was an essential tool for blood pressure ...
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