Search results
Results from the WOW.Com Content Network
Levels of copper-containing enzymes, such as cytochrome c oxidase, superoxide dismutase, and diaminase oxidase, vary not only in response to copper state but also in response to a variety of other physiological and biochemical factors and therefore are inconsistent markers of excess copper status.
Amine oxidase (copper-containing) (AOC) (EC 1.4.3.21 and EC 1.4.3.22; formerly EC 1.4.3.6) is a family of amine oxidase enzymes which includes both primary-amine oxidase and diamine oxidase; these enzymes catalyze the oxidation of a wide range of biogenic amines including many neurotransmitters, histamine and xenobiotic amines.
The metals copper, zinc, iron, and manganese are examples of metals that are essential for the normal functioning of most plants and the bodies of most animals, such as the human body. A few ( calcium , potassium , sodium ) are present in relatively larger amounts, whereas most others are trace metals , present in smaller but important amounts ...
Pages in category "Copper enzymes" The following 32 pages are in this category, out of 32 total. This list may not reflect recent changes. 0–9.
The Blue Copper Proteins, a class of Type 1 copper proteins, are small proteins containing a cupredoxin fold and a single Type I copper ion coordinated by two histidine N-donors, a cysteine thiolate S-donor and a methionine thioether S-donor. [8] In the oxidized state, the Cu +2 ion will form either a trigonal bipyramidal or tetrahedral ...
Essential for almost all living things, although in very small amounts; it is a cofactor for many classes of enzymes. [11] [50] At least one of these, mitochondrial superoxide dismutase (MnSOD), is present in all aerobic Bacteria and in the mitochondria of all eukaryotes. [51] Large doses can have toxic effects. [11] mercury: 80: 2ac
There are three spectroscopically different copper centres found in multicopper oxidases: type 1 (or blue), type 2 (or normal) and type 3 (or coupled binuclear). [ 2 ] [ 3 ] Multicopper oxidases consist of 2, 3 or 6 of these homologous domains, which also share homology with the cupredoxins azurin and plastocyanin .
In addition the four copper atoms form a planar Cu 4 ring based on three-center two-electron bonds. The copper to copper bond length is 242 pm compared to 256 pm in bulk copper. In pentamesitylpentacopper a 5-membered copper ring is formed, similar to (2,4,6-trimethylphenyl)gold, and pentafluorophenylcopper is a tetramer. [9]