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Amygdalotomy, also known as amygdalectomy, is a form of psychosurgery which involves the surgical removal or destruction of the amygdala, or parts of the amygdala.It is usually a last-resort treatment for severe aggressive behavioral disorders and similar behaviors including hyperexcitability, violent outbursts, and self-mutilation.
Amygdalin (Laetrile) is a toxic drug that is not effective as a cancer treatment". Additionally, "No controlled clinical trials (trials that compare groups of patients who receive the new treatment to groups who do not) of laetrile have been reported." [24] The side effects of laetrile treatment are the symptoms of cyanide poisoning.
S.M., sometimes referred to as SM-046, is an American woman with a peculiar type of brain damage that physiologically reduces her ability to feel fear.First described by scientists in 1994, [1] she has had exclusive and complete bilateral amygdala destruction since late childhood as a consequence of Urbach–Wiethe disease.
The amygdala is one of the best-understood brain regions with regard to differences between the sexes. The amygdala is larger in males than females, in children aged 7 to 11, [17] adult humans, [18] and adult rats. [19] There is considerable growth within the first few years of structural development in both male and female amygdalae. [20]
Changes in the composition of the gut microbiota due to diet, drugs, or disease correlate with changes in levels of circulating cytokines, some of which can affect brain function. [32] The gut microbiota also release molecules that can directly activate the vagus nerve , which transmits information about the state of the intestines to the brain.
Amygdalohippocampectomy is a surgical procedure for the treatment of epilepsy.It consists of the removal of the hippocampus, which has a role in memory, spatial awareness, and navigation, [1] and the amygdalae, which have a role in the processing and memory of emotional reactions, [2] both structures forming part of the limbic system of the brain.
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The amygdala connects to the thalamus both through the amygdalofugal pathway and through a direct connection to the dorsomedial nucleus of the thalamus. [13] After leaving the substantia innominata , the ventral amygdalofugal pathway continues on a medial path to enter the septal region, the lateral preoptic area , the hypothalamus , and the ...