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  2. Clascoterone - Wikipedia

    en.wikipedia.org/wiki/Clascoterone

    Clascoterone, sold under the brand name Winlevi, is an antiandrogen medication which is used topically in the treatment of acne. [ 5 ] [ 6 ] [ 7 ] It is also under development in a higher concentration for the treatment of androgen-dependent scalp hair loss , under the brand name Breezula . [ 6 ]

  3. Steroidal antiandrogen - Wikipedia

    en.wikipedia.org/wiki/Steroidal_antiandrogen

    A steroidal antiandrogen (SAA) is an antiandrogen with a steroidal chemical structure. [1] [2] [3] They are typically antagonists of the androgen receptor (AR) and act both by blocking the effects of androgens like testosterone and dihydrotestosterone (DHT) and by suppressing gonadal androgen production.

  4. Antiandrogen - Wikipedia

    en.wikipedia.org/wiki/Antiandrogen

    1962: Spironolactone is first reported to produce gynecomastia in men [219] [221] 1966: Benorterone is the first known antiandrogen to be studied clinically, to treat acne and hirsutism in women [ 222 ] [ 223 ]

  5. Pharmacodynamics of spironolactone - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics_of...

    Spironolactone has been identified as an inhibitor of NRG1‐ERBB4 signaling. [142] Spironolactone has been found to act as a potent inhibitor of the pannexin 1 channel, and this action appears to be involved in its antihypertensive effects independently of MR antagonism. [143] Spironolactone has been found to block hERG channels. [144]

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  8. Spironolactone - Wikipedia

    en.wikipedia.org/wiki/Spironolactone

    Spironolactone, sold under the brand name Aldactone among others, is a diuretic medication primarily used to treat fluid build-up due to heart failure, ...

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