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Therefore, it is recommended that people using this medication avoid potassium supplements and salt substitutes containing potassium. [169] Physicians must be careful to monitor potassium levels in both males and females who are taking spironolactone as a diuretic, especially during the first twelve months of use and whenever the dosage is ...
[43] [44] [45] However, in another case report, spironolactone was effective in normalizing prostate-specific antigen in a man with prostate cancer. [46] In addition, spironolactone has been studied in the treatment of prostate cancer. [47] [48] Canrenone binds to and blocks the AR in vitro. [29]
Unlike spironolactone, bicalutamide has no antimineralocorticoid activity, [97] and for this reason, has no risk of hyperkalemia (which can, rarely/in severe cases, result in hospitalization or death) [112] or other antimineralocorticoid side effects such as urinary frequency, dehydration, hypotension, hyponatremia, metabolic acidosis, or ...
F or people battling prostate cancer, the fight can feel like a contest between the disease and the doctors. Their body is the battlefield, but they may nonetheless feel marginalized—more ...
Eplerenone is a newer drug that was developed as a spironolactone analog with reduced adverse effects. In addition to the y-lactone ring and the substituent on C-7, eplerenone has a 9α,11α-epoxy group. This group is believed to be the reason why eplerenone has a 20-40-fold lower affinity for the mineralocorticoid receptor than spironolactone. [7]
"This is why, in addition to athletic enhancement, peptides have become popular in the research world for treating things like aging, obesity, cancer and diabetes," he says.
While it was once “just” a medication for people with type 2 diabetes, metformin is now thought of as a “wonder drug with multiple potentials,” says David Cutler, M.D., a family medicine ...
Bicalutamide is used primarily in the treatment of early and advanced prostate cancer. [1] It is approved at a dosage of 50 mg/day as a combination therapy with a gonadotropin-releasing hormone analogue (GnRH analogue) or orchiectomy (that is, surgical or medical castration) in the treatment of stage D2 metastatic prostate cancer (mPC), [2] [3] and as a monotherapy at a dosage of 150 mg/day ...