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  2. Pimobendan - Wikipedia

    en.wikipedia.org/wiki/Pimobendan

    Pimobendan is indicated for the management of the signs of mild, moderate, or severe congestive heart failure in dogs due to clinical myxomatous mitral valve disease (MMVD) or dilated cardiomyopathy (DCM); [1] [7] and for use with concurrent therapy for congestive heart failure (e.g.,furosemide, etc.) as appropriate on a case-by-case basis. [1]

  3. Salicylate poisoning - Wikipedia

    en.wikipedia.org/wiki/Salicylate_poisoning

    Sodium bicarbonate is given in a significant aspirin overdose (salicylate level greater than 35 mg/dL 6 hours after ingestion) regardless of the serum pH, as it enhances elimination of aspirin in the urine. It is given until a urine pH between 7.5 and 8.0 is achieved.

  4. Trolamine salicylate - Wikipedia

    en.wikipedia.org/wiki/Trolamine_salicylate

    Trolamine salicylate (Aspercreme, Aspergel) is an organic compound with the chemical formula [HN(CH 2 CH 2 OH) 3] + C 6 H 4 (OH)(COO −).It is a salt of triethanolamine and salicylic acid, i.e. the compound consists of protonated triethanolamine and the conjugate base of salicylic acid, salicate.

  5. Aspirin - Wikipedia

    en.wikipedia.org/wiki/Aspirin

    Aspirin taken at doses of ≤325 mg and ≤100 mg per day for ≥2 days can increase the odds of suffering a gout attack by 81% and 91% respectively. This effect may potentially be worsened by high purine diets, diuretics, and kidney disease, but is eliminated by the urate lowering drug allopurinol. [184]

  6. Mechanism of action of aspirin - Wikipedia

    en.wikipedia.org/wiki/Mechanism_of_action_of_aspirin

    Aspirin acts as an acetylating agent where an acetyl group is covalently attached to a serine residue in the active site of the COX enzyme. [1] This makes aspirin different from other NSAIDs (such as diclofenac and ibuprofen), which are reversible inhibitors; aspirin creates an allosteric change in the structure of the COX enzyme. [2]

  7. Aspirin-exacerbated respiratory disease - Wikipedia

    en.wikipedia.org/wiki/Aspirin-exacerbated...

    Aspirin-exacerbated respiratory disease (AERD), also called NSAID-exacerbated respiratory disease (N-ERD) or historically aspirin-induced asthma and Samter's Triad, is a long-term disease defined by three simultaneous symptoms: asthma, chronic rhinosinusitis with nasal polyps, and intolerance of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs).

  8. Carprofen - Wikipedia

    en.wikipedia.org/wiki/Carprofen

    A 100 mg Rimadyl tablet approximately 19 mm (0.75 in) wide by 8.6 mm (0.34 in) thick, as sold in the USA. Carprofen is a nonsteroidal anti-inflammatory drug (NSAID) of the carbazole and propionic acid class that was previously for use in humans and animals but is now only available to veterinarians for prescribing as a supportive treatment for various conditions in animals. [1]

  9. Median lethal dose - Wikipedia

    en.wikipedia.org/wiki/Median_lethal_dose

    The median infective dose (ID 50) is the number of organisms received by a person or test animal qualified by the route of administration (e.g., 1,200 org/man per oral). Because of the difficulties in counting actual organisms in a dose, infective doses may be expressed in terms of biological assay, such as the number of LD 50 s to some test ...

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