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  2. Tadalafil: Your Ultimate Guide to Dosages, Side Effects & More

    www.aol.com/tadalafil-ultimate-guide-dosages...

    In elderly men, for instance, tadalafil has a slightly longer half-life of roughly 21.6 hours. As a long-lasting ED medication, tadalafil is only recommended for use one time per day.

  3. Tadalafil - Wikipedia

    en.wikipedia.org/wiki/Tadalafil

    Tadalafil, sold under the brand name Cialis among others, is a medication used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension. [5] [6] [8] It is taken by mouth. [8] Onset is typically within half an hour and the duration is up to 36 hours. [8]

  4. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

    www.aol.com/ed-pill-guide-everything-know...

    Cialis (tadalafil) has a half-life of 17.5 hours, meaning this drug lasts up to 36 hours after it’s consumed. Levitra (vardenafil) ...

  5. Is It Safe to Take Cialis Daily? - AOL

    www.aol.com/safe-cialis-daily-115900442.html

    Using Cialis or generic tadalafil as needed is a good option if you typically have intimacy a few times per week — for example, every other day. ... has a long half-life, it can remain active ...

  6. Biological half-life - Wikipedia

    en.wikipedia.org/wiki/Biological_half-life

    Absorption half-life 1 h, elimination half-life 12 h. Biological half-life ( elimination half-life , pharmacological half-life ) is the time taken for concentration of a biological substance (such as a medication ) to decrease from its maximum concentration ( C max ) to half of C max in the blood plasma .

  7. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    PDE5 inhibitors are contraindicated within 24 hours (or 48 hours with tadalafil) of taking alpha-blockers, soluble guanylate cyclase stimulators, or nitrate medications such as isosorbide mononitrate or isosorbide dinitrate. [1] Concurrent use of these medications can lead to life-threatening low blood pressure. [5]

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