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Midodrine is a prodrug which forms the active metabolite, desglymidodrine, which is an α 1-adrenergic receptor agonist and exerts its actions via activation of α 1-adrenergic receptors of the arteriolar and venous vasculature, producing an increase in vascular tone and elevation of blood pressure.
Swollen legs, feet and ankles are common in late pregnancy. The problem is partly caused by the weight of the uterus on the major veins of the pelvis . It usually clears up after delivery of the baby, and is mostly not a cause for concern, [ 16 ] though it should always be reported to a doctor.
Dry eye syndrome can lead to blurred vision, instability of the tear film, increased risk of damage to the ocular surface such as scarring of the cornea, and changes in the eye including the neurosensory system. [2] [6] Dry eye occurs when either the eye does not produce enough tears or when the tears evaporate too quickly. [2]
MCTD has no specific treatment. Management should address the individual's primary issues, such as arthritis , skin disease , or visceral involvement. Low-dose glucocorticoids , nonsteroidal anti-inflammatory medications , hydroxychloroquine , or a combination of these therapies can effectively treat many patients.
In women, it is most prevalent in an upper limb after breast cancer surgery, especially axillary lymph node dissection, [15] and occurs on the same side of the body as the surgery. Breast and trunk lymphedema can also occur but go unrecognised as there is swelling in the area after surgery, and its symptoms ( peau d'orange and an inverted ...
Like other medications for the treatment of (ED), Cialis — and its generic version, tadalafil — can cause adverse effects at first. Fortunately, most tadalafil side effects are mild and ...
Tiger's eye (also called tiger eye) is a chatoyant gemstone that is usually a metamorphic rock with a golden to red-brown colour and a silky lustre.As members of the quartz group, tiger's eye and the related blue-coloured mineral hawk's eye gain their silky, lustrous appearance from the parallel intergrowth of quartz crystals and altered amphibole fibres that have mostly turned into limonite.
The conjunctiva becomes swollen and gelatinous in appearance. Often, the eye area swells so much that the eyes become difficult or impossible to close fully. [2] Sometimes, it may also appear as if the eyeball has moved slightly backwards from the white part of the eye due to the fluid filled in the conjunctiva all over the eyes except the iris.