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This single EPSP does not sufficiently depolarize the membrane to generate an action potential. The summation of these three EPSPs generates an action potential. In neuroscience, an excitatory postsynaptic potential (EPSP) is a postsynaptic potential that makes the postsynaptic neuron more likely to fire an action potential.
Neonatal hypoglycemia, or low blood sugar in newborn babies, occurs when an infant's blood glucose level is below normal. [1] Diagnostic thresholds vary internationally. In the US, hypoglycemia is when the blood glucose level is below 30 mg/dL within the first 24 hours of life and below 45 mg/dL after, but international standards differ. [2]
Motor Control: Postsynaptic potentials in motor neurons integrate signals from the brain and spinal cord to coordinate muscle movement. During voluntary movement, EPSPs activate motor neurons, while IPSPs inhibit opposing muscle groups to make sure smooth motion occurs.
Blood-sugar levels naturally fluctuate throughout the day, the body normally maintaining levels between 70 and 110 mg/dL (3.9–6.1 mmol/L). [3] [2] Although 70 mg/dL (3.9 mmol/L) is the lower limit of normal glucose, symptoms of hypoglycemia usually do not occur until blood sugar has fallen to 55 mg/dL (3.0 mmol/L) or lower.
EPSP synthase is a monomeric enzyme with a molecular mass of approximately 46,000. [2] [3] [4] It consists of two domains connected by protein strands that function as a hinge, allowing the two domains to move closer together.
More severe symptoms, such as seizures (fits or convulsions), can occur with a prolonged or extremely low blood sugar level. [24] [22] [19] [20] If the blood sugar level is not corrected, it can lead to loss of consciousness and potential brain injury. [24] A simple blood sugar measurement is essential if there are any symptoms of hypoglycaemia ...
The mother's antibodies can remain in the baby's bloodstream for weeks, and bleeding can occur in the baby before birth (fetal), during birth or after birth (neonatal). [ 9 ] A number of different proteins can cause NAIT, about 80% of cases are caused by antibodies against platelet antigen HPA -1a , 15% by anti- HPA -5b , and 5% by other ...
The incidence of hypoglycemia due to complex drug interactions, especially involving oral hypoglycemic agents and insulin for diabetes, rises with age. Though much rarer, the incidence of insulin-producing tumors also rises with advancing age. Most tumors causing hypoglycemia by mechanisms other than insulin excess occur in adults. [citation ...