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Insulin glargine sold under the brand name Lantus among others is a long-acting modified form of medical insulin, used in the management of type 1 and type 2 diabetes. [7] It is injected just under the skin . [ 7 ]
Slow-acting insulin such as Lantus or Levemir can be used for a large portion of the basal insulin needs, and the pump basal rate program can be used to fill in the remaining need. Lantus injected once daily is one back-up for pump users, but it can be a real benefit for some insulin pumpers who tend to develop ketoacidosis quickly. [citation ...
The use of subcutaneous injections of insulin is designed to mimic the natural physiological cycle of insulin secretion, while taking into account the various properties of the formulations used such as half-life, onset of action, and duration of action.
It is administered once daily and has a duration of action that lasts up to 40 hours (compared to 18 to 26 hours provided by other marketed long-acting insulins such as insulin glargine and insulin detemir). [6] [7] The change involves attachment of a hexadecanedioic acid tail to the B29 lysine's "tail" nitrogen. This allows the molecule to ...
The Psychopathology of Everyday Life. Everyday life is a key concept in cultural studies and is a specialized subject in the field of sociology.Some argue that, motivated by capitalism and industrialism's degrading effects on human existence and perception, writers and artists of the 19th century turned more towards self-reflection and the portrayal of everyday life represented in their ...
Observations of daily living (ODLs) are cues that people attend to in the course of their everyday life, that inform them about their health. [1] [2] [3]ODLs are different from signs, symptoms, and clinical indicators in that they are defined by the patient, and are not necessarily directly mapped to biomedical models of disease and illness.
In some cases, these medications may be combined into one pen to be administered daily, for example insulin degludec with liraglutide [6] and insulin glargine with lixisenatide. [11] Combination products are available in fixed-dose ratios and are generally dosed by units of insulin, which will administer a proportional amount of the GLP-1 ...
Insulin release is stimulated also by beta-2 receptor stimulation and inhibited by alpha-1 receptor stimulation. In addition, cortisol, glucagon and growth hormone antagonize the actions of insulin during times of stress. Insulin also inhibits fatty acid release by hormone-sensitive lipase in adipose tissue. [8]
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