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Recombinase polymerase amplification (RPA) is a single tube, isothermal alternative to the polymerase chain reaction (PCR). [1] By adding a reverse transcriptase enzyme to an RPA reaction, it can detect RNA as well as DNA, without the need for a separate step to produce cDNA.
Replication protein A (RPA) is the major protein that binds to single-stranded DNA (ssDNA) in eukaryotic cells. [1] [2] In vitro, RPA shows a much higher affinity for ssDNA than RNA or double-stranded DNA. [3] RPA is required in replication, recombination and repair processes such as nucleotide excision repair and homologous recombination.
Advertisement for a healthy diet to possibly reduce cancer risk. An average 35% of human cancer mortality is attributed to the diet of the individual. [9] Studies have linked excessive consumption of red or processed meat to an increased risk of breast cancer, colon cancer, and pancreatic cancer, a phenomenon which could be due to the presence of carcinogens in meats cooked at high temperatures.
If successful, this approach could lead to new ways to treat or even prevent pancreatic and other advanced cancers. MORE: Cancer vaccine with minimal side effects nearing Phase 3 clinical trials
Platz, who studies risk factors for prostate and colon cancers, takes care to avoid major spikes in blood sugar in the morning because hyperglycemia, or high blood sugar, is associated with ...
A new treatment for locally advanced rectal cancer (LARC) has proved successful enough to avoid surgery and reduce the risk of recurrence, according to a new study conducted at Uppsala University ...
Advertisement suggesting that a healthy diet helps prevent cancer. Many dietary recommendations have been proposed to reduce the risk of cancer, few have significant supporting scientific evidence. [42] [43] [44] Obesity and drinking alcohol have been correlated with the incidence and progression of some cancers. [42]
Lydia Choi, MD, a breast surgical oncologist at Barbara Ann Karmanos Cancer Institute, says it might help people to think of Stage 0 as a precancer—the abnormal cells can progress to stage 1 and ...