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9-Nor-9β-hydroxyhexahydrocannabinol (9-nor-9beta-HHC; sometimes incorrectly confused with 11-nor-9β-hydroxyhexahydrocannabinol [1]) is a cannabinoid first discovered from early modifications to the structure of THC, in a search for the simplest compound that could still fulfill the binding requirements to produce cannabis-like activity. [2] [3]
9R-HHC has an EC50 of 3.4nM ± 1.5nM at CB1 and 6.2nM ± 2.1nM at CB2 while 9S-HHC has an EC50 of 57nM ± 19nM at CB1 and 55nM ± 10nM at CB2. The same study found D9-THC to have an EC50 of 3.9nM ± 0.5nM at CB1 and 2.5nM ± 0.7nM at CB2. The EC50 shows 9R-HHC has a lower selectivity for CB2 (0.55x) compared to THC (1.5x). HHC has been ...
HHC-P is a partial agonist of the CB1 receptors with an EC50 of 44.4nM for 9R-HHCP and 134nM for 9S-HHCP. Compared to Hexahydrocannabinol (HHC) with an EC50 of 101nM for 9R-HHC and 1,190nM for 9S-HHC [ 5 ] In 2021, HHC-P was positively identified in multiple retail electronic vaping products in the United States.
The 11-OH-9β-HHC isomer is the structurally related methylene homologue of 11-Nor-9β-hydroxyhexahydrocannabinol also known as 9-Nor-9β-hydroxyhexahydrocannabinol. [8] [9] HU-243 is a synthetic analog of 11-OH-9β-HHC in which the natural n-pentyl side chain is replaced with a geminal-dimethylheptyl substitution.
For if what they produce is the Gospel of Truth, and is different from those the apostles handed down to us, those who care to can learn how it can be shown from the Scriptures themselves that [then] what is handed down from the apostles is not the Gospel of Truth. [4]
LifeWise Academy was founded in 2018 by Joel Penton, a former Ohio State defensive lineman, [3] [4] as a division of his nonprofit ministry Stand for Truth. [5] The organization was inspired by the weekday religious education program in his hometown of Van Wert, Ohio, in 2012. [3]
HOW TO USE THIS BOOK Both the public and corporate workshops are half-day events, but over the years many people have been doing the workshop on their own, usually taking about three hours to get through the 10 questions. Watching them succeed so well on their own helped me realize this really can be a simple do-it-yourself process.
"Veritas vos liberabit" in the 1890 graduation book of Johns Hopkins University "The truth will set you free" (Latin: Vēritās līberābit vōs (biblical) or Vēritās vōs līberābit (common), Greek: ἡ ἀλήθεια ἐλευθερώσει ὑμᾶς, transl. hē alḗtheia eleutherṓsei hūmâs) is a statement found in John 8:32—"And ye shall know the truth and the truth shall make ...