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N-Nitrosodimethylamine (NDMA), also known as dimethylnitrosamine (DMN), is an organic compound with the formula (CH 3) 2 NNO. It is one of the simplest members of a large class of nitrosamines. It is a volatile yellow oil. NDMA has attracted wide attention as being highly hepatotoxic and a known carcinogen in laboratory animals. [2]
The Fudan poisoning case was a criminal case in China.Lin Senhao, a graduate student at Shanghai Medical College of Fudan University, was accused of murdering his roommate Huang Yang by poisoning him with N-nitrosodimethylamine that he mixed into the water fountain at the dormitory, later claiming it was only supposed to be a prank.
Metformin is the British Approved Name (BAN), the United States Adopted Name (USAN), and the International Nonproprietary Name (INN). It is sold under several brand names. Common brand names include Glucophage, Riomet, Fortamet, and Glumetza in the US. [ 170 ]
Ketamine, one of the most popular NMDA receptor antagonists. NMDA receptor antagonists are a class of drugs that work to antagonize, or inhibit the action of, the N -Methyl- D -aspartate receptor (NMDAR). They are commonly used as anesthetics for humans and animals; the state of anesthesia they induce is referred to as dissociative anesthesia.
Rare [ 2 ] Deaths. ~4% risk of death [ 2 ] Anti-NMDA receptor encephalitis is a type of brain inflammation caused by antibodies. [ 4 ] Early symptoms may include fever, headache, and feeling tired. [ 1 ][ 2 ] This is then typically followed by psychosis which presents with false beliefs (delusions) and seeing or hearing things that others do ...
Nitrosamine. In organic chemistry, nitrosamines (or more formally N-nitrosamines) are organic compounds with the chemical structure R2N−N=O, where R is usually an alkyl group. [1] They feature a nitroso group (NO+) bonded to a deprotonated amine. Most nitrosamines are carcinogenic in nonhuman animals. [2]
The NMDA receptor is a glutamate and ion channel protein receptor that is activated when glycine and glutamate bind to it. [ 5 ] The receptor is a highly complex and dynamic heteromeric protein that interacts with a multitude of intracellular proteins via three distinct subunits, namely GluN1, GluN2, and GluN3.
NDMA may refer to: N-Nitrosodimethylamine, a semi-volatile organic compound; National Disaster Management Authority (India) National Disaster Management Authority ...