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  2. EPA list of extremely hazardous substances - Wikipedia

    en.wikipedia.org/wiki/EPA_list_of_extremely...

    This is the list of extremely hazardous substances defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act (42 U.S.C. § 11002). The list can be found as an appendix to 40 CFR 355. [1] Updates as of 2006 can be seen on the Federal Register, 71 FR 47121 (August 16, 2006). [2]

  3. List of deaths from drug overdose and intoxication - Wikipedia

    en.wikipedia.org/wiki/List_of_deaths_from_drug...

    While fatal overdoses are highly associated with drugs such as opiates, cocaine and alcohol, [ 2 ] deaths from other drugs such as caffeine are extremely rare. [ 21 ] This alphabetical list contains 634 people whose deaths can be reliably sourced to be the result of drug overdose or acute drug intoxication.

  4. Drug overdose - Wikipedia

    en.wikipedia.org/wiki/Drug_overdose

    A drug overdose (overdose or OD) is the ingestion or application of a drug or other substance in quantities much greater than are recommended. [ 2 ][ 3 ] Typically it is used for cases when a risk to health will potentially result. [ 2 ] An overdose may result in a toxic state or death. [ 3 ]

  5. Therapeutic index - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_index

    The therapeutic index (TI; also referred to as therapeutic ratio) is a quantitative measurement of the relative safety of a drug with regard to risk of overdose. It is a comparison of the amount of a therapeutic agent that causes toxicity to the amount that causes the therapeutic effect. [1] The related terms therapeutic window or safety window ...

  6. List of withdrawn drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_withdrawn_drugs

    Alpidem (Ananxyl) 1995. Worldwide. Not approved in the US, withdrawn in France in 1994 [ 4 ] and the rest of the market in 1995 because of rare but serious hepatotoxicity. [ 3 ][ 5 ] Alosetron (Lotronex) 2000. US. Serious gastrointestinal adverse events; ischemic colitis; severe constipation. [ 2 ] Reintroduced 2002 with restricted indication ...

  7. Benzodiazepine overdose - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine_overdose

    t. e. Benzodiazepine overdose (BZD OD) describes the ingestion of one of the drugs in the benzodiazepine class in quantities greater than are recommended or generally practiced. The most common symptoms of overdose include central nervous system (CNS) depression, impaired balance, ataxia, and slurred speech.

  8. Digoxin toxicity - Wikipedia

    en.wikipedia.org/wiki/Digoxin_toxicity

    Frequency. ~2,500 cases per year (US)[2] Digoxin toxicity, also known as digoxin poisoning, is a type of poisoningthat occurs in people who take too much of the medication digoxinor eat plants such as foxglovethat contain a similar substance. [1][2]Symptoms are typically vague.[1]

  9. Lithium toxicity - Wikipedia

    en.wikipedia.org/wiki/Lithium_toxicity

    Lithium toxicity, also known as lithium overdose, is the condition of having too much lithium. Symptoms may include a tremor, increased reflexes, trouble walking, kidney problems, and an altered level of consciousness. Some symptoms may last for a year after levels return to normal. Complications may include serotonin syndrome.