Search results
Results from the WOW.Com Content Network
Rivaroxaban, sold under the brand name Xarelto among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. [8] Specifically it is used to treat deep vein thrombosis and pulmonary emboli and prevent blood clots in atrial fibrillation and following hip or knee surgery. [ 8 ]
Leroy Chollet (March 5, 1925 – June 10, 1998) was an American professional basketball player. Chollet enrolled at Loyola University New Orleans and led the Loyola Wolf Pack to their first championship.
Antistasin, the first discovered naturally occurring direct Xa inhibitor Rivaroxaban, the first synthetic direct Xa inhibitor marketed as a drug Prior to the introduction of direct factor Xa inhibitors, vitamin K antagonists such as warfarin were the only oral anticoagulants for over 60 years, and together with heparin have been the main blood ...
Rivaroxaban. During the SAR development of rivaroxaban, researchers realized that adding a 5-chlorothiophene-2-carboxamide group to the oxazolidonine core could increase the potency by 200 fold, which had previously been too weak for medical use. In addition to this discovery, a clear preference for the (S)-configuration was confirmed.
In December 2019, the US FDA approved a generic version of apixaban produced jointly by Mylan and Micro Labs. [ 36 ] [ 35 ] [ 11 ] BMS and Pfizer worked quickly to block generics from being created, and in August 2020, they won a patent infringement lawsuit against Sigmapharm , Sunshine Lake, and Unichem , after previously settling patent cases ...
Skeletal formulae of the antibiotic linezolid (top) and the anticoagulant rivaroxaban (bottom), highlighting their similar oxazolidinone core (in blue). Created using ACD/ChemSketch 10.0 and Inkscape .
An anticoagulant, commonly known as a blood thinner, is a chemical substance that prevents or reduces the coagulation of blood, prolonging the clotting time. [1] Some occur naturally in blood-eating animals, such as leeches and mosquitoes, which help keep the bite area unclotted long enough for the animal to obtain blood.
This page was last edited on 4 November 2019, at 16:51 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.