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MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is an organic compound. It is classified as a tetrahydropyridine . It is of interest as a precursor to the monoaminergic neurotoxin MPP + , which causes permanent symptoms of Parkinson's disease by destroying dopaminergic neurons in the substantia nigra of the brain .
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine causes permanent symptoms of Parkinson's disease. (–)-Mitragynine is a naturally occurring tetrahydropyridine. 2,3,4,5-Tetrahydropyridine, a colorless liquid, is commercially available. It is an imine. Illustrating another isomer of tetrahydropyridine, 6-acetyl-2,3,4,5-tetrahydropyridine occurs ...
Methylphenyltetrahydropyridine N-monooxygenase (EC 1.13.12.11) is an enzyme with systematic name 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine:oxygen N-oxidoreductase. [1] This enzyme catalyses the following chemical reaction
The 3 substrates of this enzyme are succinyl-CoA, (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate, and H 2 O, whereas its two products are CoA and N-succinyl-L-2-amino-6-oxoheptanedioate. This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name ...
Hinduja Hospital, Mahim, is a not-for-profit institution, with at least 20% of its total capacity reserved for people from the economically weaker section. It has committed 10% of its total beds for subsidised / concessional treatments, and 10% beds for completely free treatments. [19] [20] [21]
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Baikiain is an organic compound with the molecular formula C 6 H 9 NO 2.Chemically, it is classified as a tetrahydropyridine substituted with a carboxylic acid.Because it contains both this carboxylic acid and an adjacent amine group, it is also an alpha-amino acid. [1]
PG is finally synthesized when a PGP phosphatase enzyme catalyzes the immediate dephosphorylation of the PGP intermediate to form PG. [4] In bacteria, another membrane phospholipid known as cardiolipin can be synthesized by condensing two molecules of phosphatidylglycerol; a reaction catalyzed by the enzyme cardiolipin-synthase. [ 5 ]