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45.4 million / 0.6% (2015, global) [5] Deaths. 107,000 (2015, global) [6] Syphilis (/ ˈsɪfəlɪs /) is a sexually transmitted infection caused by the bacterium Treponema pallidum subspecies pallidum. [1] The signs and symptoms depend on the stage it presents: primary, secondary, latent or tertiary. [1][2] The primary stage classically ...
Syphilis is curable at all stages. It is far easier to treat during the early stages of infection, often with a single dose of penicillin G. During the primary, secondary, and early-latent stages ...
The history of syphilis has been well studied, but the exact origin of the disease remains unknown. [3] It appears to have originated in both Africa and America. [4] [5] As such, there are two primary hypotheses: one proposes that syphilis was carried to Europe from the Americas by the crew(s) of Christopher Columbus as a byproduct of the Columbian exchange, while the other proposes that ...
The first effective treatment for a sexually transmitted infection was salvarsan, a treatment for syphilis. With the discovery of antibiotics , a large number of sexually transmitted infections became easily curable, and this, combined with effective public health campaigns against STIs, led to a public perception during the 1960s and 1970s ...
Paul Ehrlich. Paul Ehrlich (German: [ˈpaʊl ˈʔeːɐ̯lɪç] ⓘ; 14 March 1854 – 20 August 1915) was a Nobel Prize -winning German physician and scientist who worked in the fields of hematology, immunology and antimicrobial chemotherapy. Among his foremost achievements were finding a cure for syphilis in 1909 and inventing the precursor ...
Arsphenamine, also known as Salvarsan or compound 606, is an antibiotic drug that was introduced at the beginning of the 1910s as the first effective treatment for the deadly infectious diseases syphilis, relapsing fever, and African trypanosomiasis. [2][3] This organoarsenic compound was the first modern antimicrobial agent. [4]
Purpose. blood test for syphilis. The Venereal Disease Research Laboratory test (VDRL) is a blood test for syphilis and related non-venereal treponematoses that was developed by the eponymous US laboratory. The VDRL test is used to screen for syphilis (it has high sensitivity), whereas other, more specific tests are used to diagnose the disease.
Congenital syphilis. Notched incisors known as Hutchinson's teeth which are characteristic of congenital syphilis. Specialty. Infectious diseases. Symptoms. Rash, fever, large liver and spleen, skeletal abnormalities [1] Usual onset. Unborn baby, newborn baby or later [1] Duration.
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