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In anatomy, the meninges (/ m ə ˈ n ɪ n dʒ iː z /; [1] [2] sg. meninx / ˈ m iː n ɪ ŋ k s, ˈ m ɛ n ɪ ŋ k s /; [3] from Ancient Greek μῆνιγξ (mêninx) 'membrane') [4] are the three membranes that envelop the brain and spinal cord. In mammals, the meninges are the dura mater, the arachnoid mater, and the pia mater.
The trigeminal cave is formed by the two layers of dura mater (endosteal and meningeal) which are part of an evagination of the cerebellar tentorium near the apex of the petrous part of the temporal bone.
The meninges comprise three membranes that, together with the cerebrospinal fluid, enclose and protect the brain and spinal cord (the central nervous system). The pia mater is a delicate impermeable membrane that firmly adheres to the surface of the brain, following all the minor contours.
Aseptic meningitis is the inflammation of the meninges, a membrane covering the brain and spinal cord, in patients whose cerebral spinal fluid test result is negative with routine bacterial cultures. Aseptic meningitis is caused by viruses , mycobacteria , spirochetes , fungi , medications , and cancer malignancies. [ 1 ]
The arachnoid mater is interposed between the two other meninges, the more superficial (closer to the surface) and much thicker dura mater and the deeper pia mater, from which it is separated by the subarachnoid space. The delicate arachnoid layer is not attached to the inside of the dura but against it, and surrounds the brain and spinal cord.
The subarachnoid cisterns are spaces formed by openings in the subarachnoid space, an anatomic space in the meninges of the brain. [1] The space is situated between the two meninges, the arachnoid mater and the pia mater. These cisterns are filled with cerebrospinal fluid (CSF). [1]
The subarachnoid lymphatic-like membrane (SLYM) is a possible fourth meningeal layer that was proposed in 2023 in the brain of humans and mice. [1]The SLYM is located in the subarachnoid space, the space between the middle reticular meninges and the innermost tender meninges that lie close to the brain. [1]
MRI of the brain with contrast may show enhancement of the meninges and the subarachnoid space however MRI may also be normal. [ 6 ] [ 2 ] MRI is the preferred neuroimaging test to diagnose chronic meningitis, being more sensitive than CT of the brain, however, MRI scanners are not available in many resource-limited settings where chronic ...