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Diagram of a typical long bone showing both cortical (compact) and cancellous (spongy) bone. Haversian canals [i] (sometimes canals of Havers, osteonic canals or central canals) are a series of microscopic tubes in the outermost region of bone called cortical bone. They allow blood vessels and nerves to travel through them to supply the osteocytes.
Osteocytes synthesize sclerostin, a secreted protein that inhibits bone formation by binding to LRP5/LRP6 coreceptors and blunting Wnt signaling. [16] [7] Sclerostin, the product of the SOST gene, is the first mediator of communication between osteocytes, bone forming osteoblasts and bone resorbing osteoclasts, critical for bone remodeling. [20]
This fluid contains substances too large to be transported through the gap junctions that connect the osteocytes. In cartilage, the lacunae and hence, the chondrocytes, are isolated from each other. Materials picked up by osteocytes adjacent to blood vessels are distributed throughout the bone matrix via the canaliculi.
Diagram of a typical long bone showing both compact (cortical) and cancellous (spongy) bone. Osteons on cross-section of a bone. In osteology, the osteon or haversian system (/ h ə ˈ v ɜːr. ʒ ən /; named for Clopton Havers) is the fundamental functional unit of much compact bone.
Micrograph of cancellous bone. Cancellous bone or spongy bone, [12] [11] also known as trabecular bone, is the internal tissue of the skeletal bone and is an open cell porous network that follows the material properties of biofoams. [13] [14] Cancellous bone has a higher surface-area-to-volume ratio than cortical bone and it is less dense. This ...
Located in the main shaft of a long bone (consisting mostly of compact bone), the medullary cavity has walls composed of spongy bone (cancellous bone) and is lined with a thin, vascular membrane . [1] [2] This area is involved in the formation of red blood cells and white blood cells, and the calcium supply for bird eggshells. The area has been ...
Several of these bones merge, and in the adult primates (including humans), the endocranium is composed of only five bony elements (from front to back): [4] The ethmoid bone, lying behind the nose. The sphenoid bone, underlying the forward portion of the brain; Paired petrous part of the temporal bones, containing the inner ear structures
The ethmoid bone (/ ˈ ɛ θ m ɔɪ d /; [1] [2] from Ancient Greek: ἡθμός, romanized: hēthmós, lit. 'sieve') is an unpaired bone in the skull that separates the nasal cavity from the brain. It is located at the roof of the nose, between the two orbits. The cubical bone is lightweight due to a spongy construction.