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Chlamydophila was recognized by a number of scientists in 1999, [3] with six species in Chlamydophila and three in the original genus, Chlamydia. This was immediately seen as controversial. [4] In 2015 the Chlamydophila species were reclassified as Chlamydia. [4] The history of the classification and reclassification is as follows.
Molecular Koch's postulates are a set of experimental criteria that must be satisfied to show that a gene found in a pathogenic microorganism encodes a product that contributes to the disease caused by the pathogen. Genes that satisfy molecular Koch's postulates are often referred to as virulence factors.
In the 1990s it was shown that there are several species of Chlamydia. Chlamydia trachomatis was first described in historical records in Ebers papyrus written between 1553 and 1550 BC. [48] In the ancient world, it was known as the blinding disease trachoma. The disease may have been closely linked with humans and likely predated civilization ...
Virulence is a pathogen's or microorganism's ability to cause damage to a host. In most cases, especially in animal systems, virulence refers to the degree of damage caused by a microbe to its host. [1] The pathogenicity of an organism—its ability to cause disease—is determined by its virulence factors.
Gram-negative bacteria secrete a variety of virulence factors at host–pathogen interface, via membrane vesicle trafficking as bacterial outer membrane vesicles for invasion, nutrition and other cell-cell communications. It has been found that many pathogens have converged on similar virulence factors to battle against eukaryotic host defenses ...
Vir: Virulence "Protochlamydia amoebophila" "Sodalis glossinidius" [28] Following those abbreviations is a letter or a number. Letters usually denote a "serial number", either the chronological order of discovery or the physical order of appearance of the gene in an operon. Numbers, the rarer case, denote the molecular weight of the protein in ...
Chlamydia species produce a small amount of detectable glycogen and have two ribosomal operons. Chlamydia trachomatis is the cause of an infection commonly transmitted sexually (often referred as just "Chlamydia") and also is the cause of trachoma , an infectious eye disease, spread by eye, nose, and throat secretions.
Chlamydia pneumoniae has a complex life cycle and must infect another cell to reproduce; thus, it is classified as an obligate intracellular pathogen. The full genome sequence for C. pneumoniae was published in 1999. [6] It also infects and causes disease in koalas, emerald tree boas (Corallus caninus), iguanas, chameleons, frogs, and turtles.