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[1] [2] It is a combination of clotrimazole and betamethasone dipropionate. [1] It is applied to the skin. [1] Common side effects include paresthesia, rash, edema, and secondary infections. [1] In 2022, it was the 242nd most commonly prescribed medication in the United States, with more than 1 million prescriptions. [3] [4]
Topical clotrimazole is categorized as pregnancy category B. [15] Small amounts of clotrimazole may be absorbed systemically following topical and vaginal administration. However, topical clotrimazole is still considered safe to use to treat yeast infections in pregnant women and is a safer alternative to other antifungals. [15] [16]
Betamethasone is a steroid medication. [3] It is used for a number of diseases including rheumatic disorders such as rheumatoid arthritis and systemic lupus erythematosus, skin diseases such as dermatitis and psoriasis, allergic conditions such as asthma and angioedema, preterm labor to speed the development of the baby's lungs, Crohn's disease, cancers such as leukemia, and along with ...
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For dogs, a dose ranges from 2.75 - 5.5 mg/kg once a day. The duration of treatment is usually at least five days, longer if there is a concurrent fungal or yeast infection. [4] Maximum duration of treatment is 30 days. [3]
GABA is the major inhibitory neurotransmitter in the brain and produces anxiolytic, anticonvulsant, sedative, and hypnotic effects. Clomethiazole appears to also have another mechanism of action mediating some of its hypothermic and neuroprotective effects. [4] The oxazole homologue is also known [5] providing a little QSAR information.
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Beclometasone or beclomethasone, also known as beclomethasone dipropionate, and sold under the brand name Qvar among others, is a steroid medication. [1] It is available as an inhaler, cream, pills, and nasal spray. [2]
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