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Hypergonadotropic hypogonadism (HH), also known as primary or peripheral/gonadal hypogonadism or primary gonadal failure, is a condition which is characterized by hypogonadism which is due to an impaired response of the gonads to the gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH), and in turn a lack of sex steroid production. [1]
[1] [2] This includes the embryological development of the primary male sex organs, and the development of male secondary sex characteristics at puberty. Androgens are synthesized in the testes, the ovaries, and the adrenal glands. Androgens increase in both males and females during puberty. [3] The major androgen in males is testosterone. [4]
[9] [10] [11] Puberty that starts earlier than usual is known as precocious puberty, and puberty which starts later than usual is known as delayed puberty. Notable among the morphologic changes in size, shape, composition, and functioning of the pubertal body, is the development of secondary sex characteristics, the "filling in" of the child's ...
It found that less than 0.1% of U.S. transgender and gender diverse (TGD) adolescents were prescribed puberty blockers or gender-affirming hormones—and that not a single patient under age 12 ...
Sexual maturity is the capability of an organism to reproduce.In humans, it is related to both puberty and adulthood. [1] Puberty is the biological process of sexual maturation, while adulthood, the condition of being socially recognized as an independent person capable of giving consent and taking responsibility, generally implies sexual maturity (certain disorders of sexual development ...
As puberty begins and sex hormone levels rise, differences appear, though some changes are similar in males and females. Male levels of testosterone directly induce the growth of the genitals, and indirectly (via dihydrotestosterone (DHT)) the prostate. Estradiol and other hormones cause breasts to develop in females.
At 11 years old, I confided in my mom that I thought I was dying as I had two identical tumors forming on my chest. There was no judgment—or really any kind of reaction—for my mom’s part.
Kisspeptin-GPR54 signaling has an important role in initiating secretion of gonadotropin-releasing hormone (GnRH) at puberty, the extent of which is an area of ongoing research. [7] Gonadotropin-releasing hormone is released from the hypothalamus to act on the anterior pituitary triggering the release of luteinizing hormone (LH), and follicle ...