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Experts call vaginal estrogen "the holy grail" for its effectiveness in improving vulvar or vaginal itching and burning, painful sex and recurring UTIs.
Estrogen deprivation therapy, also known as endocrine therapy, is a form of hormone therapy that is used in the treatment of breast cancer.Modalities include antiestrogens or estrogen blockers such as selective estrogen receptor modulators (SERMs) like tamoxifen, selective estrogen receptor degraders like fulvestrant, and aromatase inhibitors like anastrozole and ovariectomy.
Women's Estrogen Lipid-Lowering Hormone Atherosclerosis Regression Trial (WELL-HART) Women's Health Initiative Estrogen Study (WHI-E) Women's Health Initiative Estrogen + Progestin Study (WHI-EP) Women's Health, Osteoporosis, Progestin, Estrogen (Women's HOPE) Women's International Study of Long-Duration Oestrogen After Menopause (WISDOM)
Observational studies of systemic HRT after breast cancer are generally reassuring. If HRT is necessary after breast cancer, estrogen-only therapy or estrogen therapy with a progestogen may be safer options than combined systemic therapy. [80] In women who are BRCA1 or BRCA2 mutation carriers, HRT does not appear to impact breast cancer risk. [81]
Diagnosis is typically based on symptoms. [1] The decrease in estrogen typically occurs following menopause. [1] Other causes may include breastfeeding or using specific medications. [1] Risk factors include smoking. [2] Treatment for atrophic vaginitis may involve the use of topical estrogen or other estrogen replacement.
According to a National Institutes of Health study, breast cancer survivors are on these medications for an average of 4.04 years. Minkin says that anywhere from five to 10 years of treatment is ...
The United States Preventive Task Force recommends that all women get screened for breast cancer every other year, starting at age 40 and continuing through age 74, to reduce their risk of dying ...
Estrone is an estrogen, specifically an agonist of the estrogen receptors (ERs) ERα and ERβ. [5] [44] It is a far less potent estrogen than is estradiol, and as such is a relatively weak estrogen. [5] [44] Given by subcutaneous injection in mice, estradiol is about 10-fold more potent than estrone and about 100-fold more potent than estriol. [45]