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The symptoms of allergic contact dermatitis are very similar to the ones caused by irritant contact dermatitis, which makes the first even harder to diagnose. The first sign of allergic contact dermatitis is the presence of the rash or skin lesion at the site of exposure. [2]
The rash appears immediately in irritant contact dermatitis; in allergic contact dermatitis, the rash sometimes does not appear until 24–72 hours after exposure to the allergen. Blisters or wheals: Blisters, wheals (welts), and urticaria (hives) often form in a pattern where skin was directly exposed to the allergen or irritant.
Stasis dermatitis, allergic contact dermatitis, acute irritant contact eczema and infective dermatitis have been documented as possible triggers, but the exact cause and mechanism is not fully understood. [7] Several other types of id reactions exist including erythema nodosum, erythema multiforme, Sweet's syndrome and urticaria. [3]
Substances that come into contact with the skin, such as latex, are also common causes of allergic reactions, known as contact dermatitis or eczema. [29] Skin allergies frequently cause rashes , or swelling and inflammation within the skin, in what is known as a " weal and flare" reaction characteristic of hives and angioedema .
Type IV hypersensitivity, in the Gell and Coombs classification of allergic reactions, often called delayed-type hypersensitivity, is a type of hypersensitivity reaction that can take a day or more to develop. [1] Unlike the other types, it is not humoral (not antibody-mediated) but rather is a type of cell-mediated response.
Eyelid dermatitis is commonly related to atopic dermatitis or allergic contact dermatitis. [1] Volatile substances, tosylamide/formaldehyde resin, epoxy hardeners, insect repellent sprays, and lemon peel oil may be implicated, with many cases of eyelid contact dermatitis being caused by substances transferred by the hands to the eyelids. [1]
Allergic contact dermatitis occurs upon exposure to an allergen, causing a hypersensitivity reaction in the skin. [ 1 ] Prevention of atopic dermatitis is typically with essential fatty acids , [ 4 ] and may be treated with moisturizers and steroid creams. [ 5 ]
"Distribution" refers to how lesions are localized. They may be confined to a single area (a patch) or may be in several places. Some distributions correlate with the means by which a given area becomes affected. For example, contact dermatitis correlates with locations where allergen has elicited an allergic immune response.