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Rovsing's sign, named after the Danish surgeon Niels Thorkild Rovsing (1862–1927), [1] is a sign of appendicitis.If palpation of the left lower quadrant of a person's abdomen increases the pain felt in the right lower quadrant, the patient is said to have a positive Rovsing's sign and may have appendicitis.
Valentino's syndrome is pain presenting in the right lower quadrant of the abdomen caused by a duodenal ulcer with perforation through the retroperitoneum. [1]It is named after Rudolph Valentino, an Italian actor, who presented with right lower quadrant pain in New York, which turned out to be a perforated peptic ulcer.
If abdominal pain or signs of peritonitis are localised in the LLQ, colitis, diverticulitis, ureteral colic or pain due to ovarian cysts or pelvic inflammatory disease may be suspected. Examples of tumors in the left lower quadrant include colon cancer and ovarian tumor. The LUQ may be painful or tender in the case of intestinal malrotation.
FMTC = familial medullary thyroid cancer Micrograph of a medullary thyroid carcinoma, as may be seen in MEN 2A and MEN 2B. H&E stain. MEN 2B is sometimes known as MEN 3 and the designation varies by institution (c.f. www.ClinicalReview.com). Although a variety of additional eponyms have been proposed for MEN2B (e.g. Williams-Pollock syndrome ...
The table in the multiple endocrine neoplasia article lists the genes involved in the various MEN syndromes. Most cases of MEN2 derive from a variation in the RET proto-oncogene, and are specific for cells of neural crest origin. A database of MEN-implicated RET mutations is maintained by the University of Utah Department of Physiology. [4]
Between 40 and 80 percent of patients with cancer pain experience neuropathic pain. [1]Brain. Brain tissue itself contains no nociceptors; brain tumors cause pain by pressing on blood vessels or the membrane that encapsulates the brain (the meninges), or indirectly by causing a build-up of fluid that may compress pain-sensitive tissue.
The few studies so far conducted into catastrophizing in cancer pain have suggested that it is associated with higher levels of pain and psychological distress. People with cancer pain who accept that pain will persist and nevertheless are able to engage in a meaningful life were less susceptible to catastrophizing and depression in one study.
Penile cancer is a rare cancer in developed nations, with annual incidence varying from 0.3 to 1 per 100,000 per year, accounting for around 0.4–0.6% of all malignancies. [4] The annual incidence is approximately 1 in 100,000 men in the United States, [28] 1 in 250,000 in Australia, [29] and 0.82 per 100,000 in Denmark. [30]