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Lipoatrophy is the term describing the localized loss of fat tissue. This may occur as a result of subcutaneous injections of insulin in the treatment of diabetes , from the use of human growth hormone or from subcutaneous injections of copaxone used for the treatment of multiple sclerosis .
A more specific term, lipoatrophy (from Greek lipo 'fat' and dystrophy 'abnormal or degenerative condition'), is used when describing the loss of fat from one area (usually the face). This condition is also characterized by a lack of circulating leptin which may lead to osteosclerosis .
Lipoatrophy Small dents in the skin that form when a person keeps injecting the needle in the same spot. See also: Lipodystrophy. Lipodystrophy Lumps or small dents in the skin that form when a person keeps injecting the needle in the same spot. Low The state of having low blood sugar.
In a sense, the "opposite" of injection site lipohypertrophy is injection site lipoatrophy, in which the subcutaneous fat around an injected area "melts away" over a few weeks or months, leaving unsightly, well-demarcated depressions in the skin. The mechanism of this local lipoatrophy is not understood and may involve autoimmunity or local ...
Iglesias P, Alvarez Fidalgo P, Codoceo R, Díez J (2004). "Lipoatrophic diabetes in an elderly woman: clinical course and serum adipocytokine concentrations".
Congenital generalized lipodystrophy (also known as Berardinelli–Seip lipodystrophy) is an extremely rare autosomal recessive condition, characterized by an extreme scarcity of fat in the subcutaneous tissues. [2]
HIV-associated lipodystrophy commonly presents with fat loss in face, buttocks, arms and legs. [citation needed]There is also fat accumulation in various body parts. . Patients often present with "buffalo hump"-like fat deposits in their up
Involutional lipoatrophy is a cutaneous condition, and is an idiopathic lipoatrophy characterized clinically by non-inflammatory focal loss of fat. [1]Idiopathic localized involutional lipoatrophy (ILIL) is a rare and nosologically imprecise condition characterized by a focal loss of subcutaneous tissue on one or several sites, occurring without any significant triggering factor or auto-immune ...