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A cellular model is a mathematical model of aspects of a biological cell, for the purposes of in silico research. Developing such models has been a task of systems biology and mathematical biology. It involves developing efficient algorithms, data structures, visualization and communication tools to orchestrate the integration of large ...
Fluid mosaic model of a cell membrane. The fluid mosaic model explains various characteristics regarding the structure of functional cell membranes.According to this biological model, there is a lipid bilayer (two molecules thick layer consisting primarily of amphipathic phospholipids) in which protein molecules are embedded.
Cell-based models are mathematical models that represent biological cells as discrete entities. Within the field of computational biology they are often simply called agent-based models [1] of which they are a specific application and they are used for simulating the biomechanics of multicellular structures such as tissues. to study the influence of these behaviors on how tissues are organised ...
OpenWorm. OpenWorm is an international open science project for the purpose of simulating the roundworm Caenorhabditis elegans at the cellular level. [1][2][3] Although the long-term goal is to model all 959 cells of the C. elegans, the first stage is to model the worm's locomotion by simulating the 302 neurons and 95 muscle cells.
The Human Cell Atlas is a global project to describe all cell types in the human body. [1] The initiative was announced by a consortium after its inaugural meeting in London in October 2016, which established the first phase of the project. [2][3] Aviv Regev and Sarah Teichmann defined the goals of the project at that meeting, [4] which was ...
Singer and Nicolson's fluid mosaic model (1972) In 1972, S. Jonathan Singer and Garth Nicolson developed new ideas for membrane structure. Their proposal was the fluid mosaic model, which is one of the dominant models now. It has two key features—a mosaic of proteins embedded in the membrane, and the membrane being a fluid bi-layer of lipids.
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Modelling biological systems is a significant task of systems biology and mathematical biology. [a] Computational systems biology[b][1] aims to develop and use efficient algorithms, data structures, visualization and communication tools with the goal of computer modelling of biological systems. It involves the use of computer simulations of ...