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Aldosterone is the primary of several endogenous members of the class of mineralocorticoids in humans. [citation needed] Deoxycorticosterone is another important member of this class. Aldosterone tends to promote Na + and water retention, and lower plasma K + concentration by the following mechanisms:
Renal physiology (Latin renes, "kidneys") is the study of the physiology of the kidney. This encompasses all functions of the kidney, including maintenance of acid-base balance; regulation of fluid balance; regulation of sodium, potassium, and other electrolytes; clearance of toxins; absorption of glucose, amino acids, and other small molecules ...
Metabolic alkalosis is an acid-base disorder in which the pH of tissue is elevated beyond the normal range (7.35–7.45). This is the result of decreased hydrogen ion concentration, leading to increased bicarbonate (HCO−3), or alternatively a direct result of increased bicarbonate concentrations. The condition typically cannot last long if ...
It regulates pH by absorbing bicarbonate and secreting protons (H +) into the filtrate, or by absorbing protons and secreting bicarbonate into the filtrate. Sodium and potassium levels are controlled by secreting K + and absorbing Na +. Sodium absorption by the distal tubule is mediated by the hormone aldosterone. Aldosterone increases sodium ...
Function. Diagram outlining movement of ions in nephron, with the collecting ducts on the right. The collecting duct system is the final component of the kidney to influence the body's electrolyte and fluid balance. In humans, the system accounts for 4–5% of the kidney's reabsorption of sodium and 5% of the kidney's reabsorption of water.
The renin-angiotensin system (RAS), or renin-angiotensin-aldosterone system (RAAS), is a hormone system that regulates blood pressure, fluid, and electrolyte balance, and systemic vascular resistance. [2][3] When renal blood flow is reduced, juxtaglomerular cells in the kidneys convert the precursor prorenin (already present in the blood) into ...
Hyperaldosteronism is a medical condition wherein too much aldosterone is produced. High aldosterone levels can lead to lowered levels of potassium in the blood (hypokalemia) and increased hydrogen ion excretion (alkalosis). Aldosterone is normally produced in the adrenal glands. Primary aldosteronism is when the adrenal glands are too active ...
In renal physiology, renal sodium reabsorption refers to the process by which the kidneys, having filtered out waste products from the blood to be excreted as urine, re-absorb sodium ions (Na2+) from the waste. It uses Na-H antiport, Na-glucose symport, sodium ion channels (minor). [1] It is stimulated by angiotensin II and aldosterone, and ...