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Lonapegsomatropin, sold under the brand name Skytrofa, is a human growth hormone used for the treatment of growth hormone deficiency. [1] [3] Lonapegsomatropin is a prodrug of somatropin.
Somapacitan should not be used in people with active malignancy, any stage of diabetic eye disease in which high blood sugar levels cause damage to blood vessels in the retina, acute critical illness, or those with acute respiratory failure, because of the increased risk of mortality with use of pharmacologic doses of somapacitan in critically ill individuals without growth hormone deficiency.
Somatrem is a recombinant human growth hormone used for the treatment of short stature due to decreased or absent secretion of endogenous growth hormone.
The main growth hormone produced by recombinant DNA technology has the approved generic name somatropin and the brand name Humatrope [4] and is properly abbreviated rhGH in the scientific literature. Since its introduction in 1992, Humatrope has been a banned sports doping agent [ 5 ] and in this context is referred to as HGH.
Saizen is a commercial preparation of synthetic somatropin (growth hormone, a.k.a. GH) used for growth hormone treatment.Manufactured by Merck Serono, Saizen is produced by recombinant DNA technology from a mammalian cell line (mouse C127) that was modified by the addition of the human GH gene, resulting in an identical 191-amino acid sequence and structure.
In many cases, women are prescribed a male testosterone product, which can be more than 50 times the recommended female dose. ‘They are often told to use a “pea-sized” blob, ...
The effects saturate with low levels of exposure, so that the effects of low-dose exposure are similar to high-dose effects. Continued use of nicotine could also lead to DNA damage and thereby ...
Recombinant growth hormone available in the U.S. (and their manufacturers) include Nutropin , Humatrope (Eli Lilly and Company), Genotropin (Pfizer), Norditropin (Novo Nordisk), Tev-Tropin and Saizen (Merck Serono). The products are nearly identical in composition, efficacy, and cost, varying primarily in the formulations and delivery devices.
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