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Bicalutamide is used primarily in the treatment of early and advanced prostate cancer. [1] It is approved at a dosage of 50 mg/day as a combination therapy with a gonadotropin-releasing hormone analogue (GnRH analogue) or orchiectomy (that is, surgical or medical castration) in the treatment of stage D2 metastatic prostate cancer (mPC), [2] [3] and as a monotherapy at a dosage of 150 mg/day ...
In the EPC trial, in which bicalutamide monotherapy (150 mg/day) was evaluated for treatment of early prostate cancer in 8,113 men, the incidence of abnormal liver function tests at 3-year median follow-up was 3.4% for bicalutamide plus standard care (n=4,052) and 1.9% for standard care alone (n=4,061).
Bicalutamide is a diarylpropionamide while flutamide is a monoarylpropionamide and nilutamide is a hydantoin. [256] Bicalutamide and flutamide, though not nilutamide, can also be classified as toluidides. [248] All three of the compounds share a common 3-trifluoromethyl aniline moiety. [257]
Gender-affirming care is a multidisciplinary approach that includes medically necessary and scientific evidence-based practices to help a person safely transition from their assigned gender ...
Gender-affirming care includes social or legal transitions, and some people might never even seek medical intervention. Hearst Owned “Every patient’s unique, and what’s necessary, required ...
New York Attorney General Letitia James sent a letter to health care providers, calling on medical institutions to continue providing gender-affirming care amid reports, according the attorney ...
In a study of 133 transgender women 61% stated that no health care provider discussed sperm banking prior to their hormone therapy or surgery. [71] In another study, 70 transgender males cited barriers such as the perceived cost of treatment (36%), need for discontinuation or delay of hormonal therapy (19%), and worsening gender dysphoria with ...
It is a rather competitive category, but high on the list of the most Orwellian newspeak terms of the 21st Century is "gender-affirming care."This vile euphemism seeks to hide the fact that what ...
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