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Example representation of the environmental factors characterizing the exposome. The exposome is a concept used to describe environmental exposures that an individual encounters throughout life, and how these exposures impact biology and health. It encompasses both external and internal factors, including chemical, physical, biological, and ...
The Toxin and Toxin-Target Database (T3DB), [1] [2] also known as the Toxic Exposome Database, is a freely accessible online database of common substances that are toxic to humans, along with their protein, DNA or organ targets. The database currently houses nearly 3,700 toxic compounds or poisons described by nearly 42,000 synonyms.
The exposome encompasses the set of human environmental (i.e. non-genetic) exposures from conception onwards, complementing the genome. The exposome was first proposed in 2005 by cancer epidemiologist Christopher Paul Wild in an article entitled "Complementing the genome with an "exposome": the outstanding challenge of environmental exposure ...
Here are nine of some of the most significant archaeological discoveries in history that changed what humans know about our origins and culture through time. Pompeii and Herculaneum gave a glimpse ...
Human history or world history is the record of humankind from prehistory to the present. Modern humans evolved in Africa around 300,000 years ago and initially lived as hunter-gatherers . They migrated out of Africa during the Last Ice Age and had spread across Earth's continental land except Antarctica by the end of the Ice Age 12,000 years ago.
An archaeological site in Ethiopia has revealed that a population of humans survived the eruption of Sumatra’s Mount Toba 74,000 years ago. One of the largest eruptions in Earth’s history ...
Spontaneous order, also named self-organization in the hard sciences, is the spontaneous emergence of order out of seeming chaos. The term "self-organization" is more often used for physical changes and biological processes, while "spontaneous order" is typically used to describe the emergence of various kinds of social orders in human social networks from the behavior of a combination of self ...
Exposome-NL is a 10-year Dutch research program of multiple Dutch universities collaborating in the field of exposome research. Researchers from fields such as exposure science, environmental science, cardiovascular and metabolic health, clinical epidemiology, nutritional epidemiology, geosciences, agent-based modelling, molecular biology, chemistry and bioinformatics, and biostatistics ...