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Differential diagnosis of an enlarged Virchow's node includes lymphoma, various intra-abdominal malignancies, breast cancer, and infection (e.g. of the arm). Similarly, an enlarged right supraclavicular lymph node tends to drain thoracic malignancies such as lung and esophageal cancer, as well as Hodgkin's lymphoma.
Lung cancer most commonly metastasizes to the brain, bones, liver, and adrenal glands. [14] Lung cancer can often appear as a solitary pulmonary nodule on a chest radiograph or CT scan. In lung cancer screening studies as many as 30% of those screened have a lung nodule, the majority of which turn out to be benign. [15]
These lymph nodes are also known as glands or lymphoid tissue. If they detect something foreign passing through them, they enlarge. This is called lymphadenopathy or swollen glands. Usually this is localized (for example, an infected spot on the scalp will cause lymph nodes in the neck on
Adenopathy, swollen lymph nodes, swollen glands: A CT scan of axillary lymphadenopathy in a 57-year-old man with multiple myeloma. Specialty: Infectious disease, oncology: Symptoms: Fever; Hard, fixed, rapidly growing nodes, indicating a possible cancer or lymphoma; night sweats; runny nose; sore throat: Causes
However, since different forms of malignant tumors generally exhibit diverse genetic, biological, and clinical properties — including response to treatment — accurate classification of lung cancer cases are critical to assuring that patients with lung cancer receive optimum management. [5] [6]
In a radiographic study of almost 2,000 lung cancer patients published 50 years ago, 3.4% of lung carcinomas proved to be cavitated masses, [34] most of which were squamous cell carcinoma. In a number of cases of severe cavitation, the resected tumor remnant consists of only a thin rim of proliferating cells.
Lung cancer is responsible for 1.3 million deaths worldwide annually and is the most common cause of cancer-related death in men and the second most common in women. According to the World Health Organization, lung cancer was responsible for approximately 10 million deaths in 2020. [2]
Lung tumor; A chest X-ray showing a tumor in the lung (marked by arrow) Specialty: Oncology Pulmonology: Symptoms: Coughing (including coughing up blood), weight loss, shortness of breath, chest pains [1] Complications: Lung cancer: Causes: Smoking Radon gas Asbestos Air pollution Genetics