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  2. Clinical pathology - Wikipedia

    en.wikipedia.org/wiki/Clinical_pathology

    Clinical chemistry: an automated blood chemistry analyser. Clinical pathology is a medical specialty that is concerned with the diagnosis of disease based on the laboratory analysis of bodily fluids , such as blood , urine , and tissue homogenates or extracts using the tools of chemistry , microbiology , hematology , molecular pathology , and ...

  3. Laboratory quality control - Wikipedia

    en.wikipedia.org/wiki/Laboratory_quality_control

    The distance from the mean is measured in standard deviations. It is named after Stanley Levey and E. R. Jennings, pathologists who suggested in 1950 that Shewhart's individuals control chart could be used in the clinical laboratory. [5] The date and time, or more often the number of the control run, is plotted on the x-axis.

  4. Clinical chemistry - Wikipedia

    en.wikipedia.org/wiki/Clinical_chemistry

    A clinical chemistry analyzer; hand shows size. Clinical chemistry (also known as chemical pathology, clinical biochemistry or medical biochemistry) is a division in medical laboratory sciences focusing on qualitative tests of important compounds, referred to as analytes or markers, in bodily fluids and tissues using analytical techniques and specialized instruments. [1]

  5. Jaffe reaction - Wikipedia

    en.wikipedia.org/wiki/Jaffe_reaction

    The Jaffe reaction is a colorimetric method used in clinical chemistry to determine creatinine levels in blood and urine. In 1886, Max Jaffe (1841–1911) wrote about its basic principles in the paper Über den Niederschlag, welchen Pikrinsäure in normalem Harn erzeugt und über eine neue Reaction des Kreatinins in which he described the properties of creatinine and picric acid in an alkaline ...

  6. Automated analyser - Wikipedia

    en.wikipedia.org/wiki/Automated_analyser

    The AutoAnalyzer is an early example of an automated chemistry analyzer using a special flow technique named "continuous flow analysis (CFA)", invented in 1957 by Leonard Skeggs, PhD and first made by the Technicon Corporation. The first applications were for clinical (medical) analysis.

  7. Medicinal chemistry - Wikipedia

    en.wikipedia.org/wiki/Medicinal_chemistry

    The synthetic chemistry specialization in medicinal chemistry aimed at adaptation and optimization of the synthetic route for industrial scale syntheses of hundreds of kilograms or more is termed process synthesis, and involves thorough knowledge of acceptable synthetic practice in the context of large scale reactions (reaction thermodynamics ...

  8. Molecular diagnostics - Wikipedia

    en.wikipedia.org/wiki/Molecular_diagnostics

    NGS assays, however, are still at an early stage in clinical diagnostics. [48] To do the molecular diagnostic test for cancer, one of the significant issue is the DNA sequence variation detection. Tumor biopsy samples used for diagnostics always contain as little as 5% of the target variant as compared to wildtype sequence.

  9. Glossary of clinical research - Wikipedia

    en.wikipedia.org/wiki/Glossary_of_clinical_research

    Clinical researchers may also do research on how health care practices affect health and disease. (NCI) Clinical series A case series in which the patients receive treatment in a clinic or other medical facility. (NCI) Clinical study or Clinical trial. A type of research study that tests how well new medical approaches work in people.