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Caffeine dependence is a condition characterized by a set of criteria, including tolerance, withdrawal symptoms, persistent desire or unsuccessful efforts to control use, and continued use despite knowledge of adverse consequences attributed to caffeine. [1] It can appear in physical dependence or psychological dependence, or both.
The person could suffer from severe symptoms of caffeine withdrawal including headaches, fatigue, and difficulty concentrating. It is recommended that the person reduces caffeine consumption gradually to avoid withdrawal as attempts to suddenly discontinue all caffeine consumption are frequently abandoned due to the severity of the withdrawal ...
Abrupt withdrawal from other drugs, such as opioids can cause an extremely painful withdrawal that is very rarely fatal in patients of general good health and with medical treatment, but is more often fatal in patients with weakened cardiovascular systems; toxicity is generally caused by the often-extreme increases in heart rate and blood ...
A growing chorus of concerned former caffeine “addicts” are trying to wake people up to the substance’s negative effects.
Here's what immunologists say.
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[31] [32] At high doses, typically greater than 300 mg, caffeine can both cause and worsen anxiety. [33] For some people, discontinuing caffeine use can significantly reduce anxiety. [34] Caffeine-induced anxiety disorder is a subclass of substance- or medication-induced anxiety disorder. [35]
Any continued use of drugs or alcohol may increase anxiety, psychosis, and depression levels in some individuals. In almost all cases drug-induced psychiatric disorders fade away with prolonged abstinence, although permanent damage to the brain and nervous system may be caused by continued substance use. [10]