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Consumer alcohol-based hand sanitizers, and health care "hand alcohol" or "alcohol hand antiseptic agents" exist in liquid, foam, and easy-flowing gel formulations. Products with 60% to 95% alcohol by volume are effective antiseptics. Lower or higher concentrations are less effective; most products contain between 60% and 80% alcohol.
Consistency and viscosity affect the adhesion and retention property of the gel, and are important in ensuring the gel is retained at the site of application and effective delivery of the drug. [3] The ingredients in topical gel formulation can be broadly categorized into four types: gelator, solvent, drug, and excipients.
Under its alternative name of "wintergreen oil", methyl salicylate is a common additive to North American rubbing alcohol products. [4] Individual manufacturers are permitted to use their own formulation standards in which the ethanol content for retail bottles of rubbing alcohol is labeled as and ranges from 70 to 99% v/v. [5]
Sloan's Liniment, right, was once a popular over-the-counter drug. Liniment (from Latin: linere, meaning "to anoint"), also called embrocation and heat rub, is a medicated topical preparation for application to the skin.
A medical professional administering nose drops Instillation of eye drops. A topical medication is a medication that is applied to a particular place on or in the body. Most often topical medication means application to body surfaces such as the skin or mucous membranes to treat ailments via a large range of classes including creams, foams, gels, lotions, and ointments. [1]
A bottle of Purell. Purell is an American brand of hand sanitizer invented in 1988, and introduced to the consumer market in 1997, by GOJO Industries. [1] Its primary component is ethyl alcohol (70% v/v), and is used by wetting one's hands thoroughly with the product, then briskly rubbing one's hands together until dry.
Polyvinyl alcohol (PVOH, PVA, or PVAl) is a water-soluble synthetic polymer. It has the idealized formula [CH 2 CH(OH)] n . It is used in papermaking , textile warp sizing , as a thickener and emulsion stabilizer in polyvinyl acetate (PVAc) adhesive formulations, in a variety of coatings, and 3D printing .
The first step of the sol-gel process is the creation of a colloidal suspension of solid particles known as a "sol". The precursors are a liquid alcohol such as ethanol which is mixed with a silicon alkoxide, such as tetramethoxysilane (TMOS), tetraethoxysilane (TEOS), and polyethoxydisiloxane (PEDS) (earlier work used sodium silicates). [24]
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