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A dendritic cell (DC) is an antigen-presenting cell (also known as an accessory cell) of the mammalian immune system.A DC's main function is to process antigen material and present it on the cell surface to the T cells of the immune system.
Plasmacytoid dendritic cells (pDCs) are a rare type of immune cell that are known to secrete large quantities of type 1 interferon (IFNs) in response to a viral infection. [1] They circulate in the blood and are found in peripheral lymphoid organs .
There are two dendritic cells subtypes; plasmacytoid (pDC) and myeloid (mDC) dendritic cells. pDCs are found within the blood and are able to cross present antigens directly or from neighboring apoptotic cells, but the main physiological significance of pDCs is the secretion of type I IFN in response to viral infections.
Dendritic cells are named after their structure that resembles that of a dendrite of an axon, and they have two vital functions: display antigens, which are recognized by T cells and alert lymphocytes of the presence of an injury or infection. When the body is introduced to infection or injury, dendritic cells migrate to immune or lymphoid ...
This is a list of immune cells, also known as white blood cells, white cells, leukocytes, ... Dendritic cell: Monocyte: Dendritic cell: DC; Cellula dendritiformis; 10-15
Blastic plasmacytoid dendritic cell neoplasm is an aggressive malignancy with features of cutaneous lymphoma (e.g. malignant plasmacytoid dendritic cell infiltrations into the skin to form single or multiple lesions) and/or leukemia (i.e. malignant plasmacytoid dendritic cells in blood and bone marrow). [2]
A dendritic cell. Dendritic cells are specialized antigen-presenting cells that have long outgrowths called dendrites, [87] that help to engulf microbes and other invaders. [88] [89] Dendritic cells are present in the tissues that are in contact with the external environment, mainly the skin, the inner lining of the nose, the lungs, the stomach ...
A peripheral blood mononuclear cell (PBMC) is any peripheral blood cell having a round nucleus. [1] These cells consist of lymphocytes (T cells, B cells, NK cells) and monocytes, whereas erythrocytes and platelets have no nuclei, and granulocytes (neutrophils, basophils, and eosinophils) have multi-lobed nuclei. In humans, lymphocytes make up ...
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