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However, the majority of patients with pancreatic cancer present with metastatic or locally advanced un-resectable disease; [7] thus only 15–20% of patients are candidates for the Whipple procedure. Surgery may follow neoadjuvant chemotherapy, which aims to shrink the tumor and increase the likelihood of complete resection. [8]
Among common consequences of complete or nearly complete pancreatectomy are deficiencies of pancreatic endocrine or exocrine function requiring replacement of insulin or digestive enzymes. The patient immediately develops type 1 diabetes, with little hope for future type 1 diabetes treatments involving the restoration of endocrine function to a ...
Pancreatic cancer can be treated with surgery, radiotherapy, chemotherapy, palliative care, or a combination of these. [1] Treatment options are partly based on the cancer stage. [1] Surgery is the only treatment that can cure pancreatic adenocarcinoma, [12] and may also be done to improve quality of life without the potential for cure.
Allen Oldfather Whipple (September 2, 1881 – April 6, 1963) was an American surgeon who is known for the pancreatic cancer operation which bears his name (the Whipple procedure) as well as Whipple's triad. Whipple was born to missionary parents William Levi Whipple and Mary Louise Whipple (née Allen), in Urmia, West Azerbaijan, Iran.
Pancreas. Frey's procedure is a surgical technique used in the treatment of chronic pancreatitis in which the diseased portions of the pancreas head are cored out. A lateral pancreaticojejunostomy (LRLPJ) is then performed in which a loop of the jejunum is then mobilized and attached over the exposed pancreatic duct to allow better drainage of the pancreas, including its head.
Another 2014 review found that adherence to the Mediterranean diet was associated with a decreased risk of death from cancer. [27] A 2017 review found a decreased rate of cancer, although evidence was weak. [28] An updated review in 2021 found that the Mediterranean diet is associated with a 13% lower risk of cancer mortality in the general ...
One of the problems that can lead to failure of the Puestow procedure is that pain can persist due to failure to drain the pancreatic duct on the head of the pancreas. A Frey's procedure is an alternative surgical procedure to the Puestow that allows for better drainage of the head, but pancreatic tissue is removed.
Although intraductal papillary mucinous neoplasms are benign tumors, they can progress to pancreatic cancer. [1] As such IPMN is viewed as a precancerous condition. [3] Once an intraductal papillary mucinous neoplasm has been found, the management options include close monitoring and pre-emptive surgery. [medical citation needed]