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An acral nevus is a cutaneous condition of the palms, soles, fingers, or toes (peripheral body parts), characterized by a skin lesion that is usually macular or only slightly elevated, and may display a uniform brown or dark brown color, often with linear striations. [1]: 1726. Acral nevi may occur in all ethnic groups, but are more common in ...
Melanocytic nevus. A melanocytic nevus (also known as nevocytic nevus, nevus-cell nevus and commonly as a mole) [1][2] is usually a noncancerous condition of pigment-producing skin cells. It is a type of melanocytic tumor that contains nevus cells. [2] A mole can be either subdermal (under the skin) or a pigmented growth on the skin, formed ...
Acral lentiginous melanoma. Acral lentiginous melanoma is a type of skin cancer. [6] It typically begins as a uniform brownish mark before becoming darker and wider with a blurred irregular edge, most frequently seen in the foot of a person with darker skin. [6] It may become bumpy and ulcerate. [6]
Some melanocytic nevi, and melanoma-in-situ (lentigo maligna) have resolved with an experimental treatment, imiquimod (Aldara) topical cream, an immune enhancing agent. In view of the very poor cure rate with standard excision, some surgeons combine the two methods: surgical excision of the lesion, then three months treatment of the area with ...
Deaths. 59,800 (2015) [ 6 ] Melanoma is the most dangerous type of skin cancer; it develops from the melanin -producing cells known as melanocytes. [ 1 ] It typically occurs in the skin, but may rarely occur in the mouth, intestines, or eye (uveal melanoma). [ 1 ][ 2 ] In women, melanomas most commonly occur on the legs; while in men, on the ...
Dysplastic nevus syndrome, also known as familial atypical multiple mole–melanoma (FAMMM) syndrome, is an inherited cutaneous condition described in certain families, and characterized by unusual nevi and multiple inherited melanomas. [2][3] First described in 1820, the condition is inherited in an autosomal dominant pattern, and caused by ...
Lentigo. A lentigo (/ lɛnˈtaɪɡoʊ /) (plural lentigines, / lɛnˈtɪdʒɪniːz /) is a small pigmented spot on the skin with a clearly defined edge, surrounded by normal-appearing skin. It is a harmless (benign) hyperplasia of melanocytes which is linear in its spread. This means the hyperplasia of melanocytes is restricted to the cell ...
Lentigo maligna melanoma. Lentigo maligna melanoma is a melanoma that has evolved from a lentigo maligna, [1]: 695 as seen as a lentigo maligna with melanoma cells invading below the boundaries of the epidermis. [2] They are usually found on chronically sun damaged skin such as the face and the forearms of the elderly.