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Proponents of orthomolecular medicine counter that some vitamins and nutrients are now used in medicine as treatments for specific diseases, such as megadose niacin and fish oil for dyslipidemias, and megavitamin therapies for a group of rare inborn errors of metabolism. [21]
However, a 2009 review of the literature found that the common perception was that pharmacists should be involved in the OTC counseling process for dietary supplements where dietary supplements are sold. [13] As experts in drug therapies that cause vitamin depletion, there are several recommendations that pharmacists commonly make.
Currently, the only option for curing OTC deficiency is a liver transplant, which restores normal enzyme activity. [10] A 2005 review of 51 patients with OTC deficiency who underwent liver transplant estimated 5-year survival rates of greater than 90%. [10] Severe cases of OTC deficiency are typically evaluated for liver transplant by 6 months ...
A 2007 meta-analysis found that animal-assisted therapy was associated with "a moderate improvement in autism spectrum symptoms". [92] Reviews of published dolphin-assisted therapy (DAT) studies found important methodological flaws and concluded that there is no compelling scientific evidence that DAT is a legitimate therapy or that it affords ...
Autism spectrum disorder [a] (ASD), or simply autism, is a neurodevelopmental disorder "characterized by persistent deficits in social communication and social interaction across multiple contexts" and "restricted, repetitive patterns of behavior, interests, or activities". [11] Sensory abnormalities are also included in the diagnostic manuals ...
Beginning in the 1930s in Canada, a megadose vitamin E therapy for cardiovascular and circulatory complaints was developed by Evan Shute and colleagues, named the "Shute protocol". [15] Tentative experiments in the 1930s by Claus W. Jungeblut [ 16 ] with larger doses of vitamin C led to Frederick Klenner's development of megadose intravenous ...
Phenol sulfur transferase deficiency, in short PST deficiency, is the lack or the reduced activity of the functional enzyme phenol sulfur transferase, which is crucial in the detoxification of mainly phenolic compounds by catalysing the sulfate conjugation of the hydroxyl groups in the toxic phenolic compounds to result in more hydrophilic forms for more efficient excretion.
In 2016, the American Medical Association adopted a policy to discourage prescriptions of nootropics for healthy people, on the basis that the cognitive effects appear to be highly variable among individuals, are dose-dependent, and limited or modest at best. [16] Piracetam, noopept and meclofenoxate have been sold as dietary supplements. [2 ...