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For this reason, the blood flow velocity is the fastest in the middle of the vessel and slowest at the vessel wall. In most cases, the mean velocity is used. [18] There are many ways to measure blood flow velocity, like videocapillary microscoping with frame-to-frame analysis, or laser Doppler anemometry. [19]
As the blood moves into the aortic arch, the area with the highest velocity tends to be on the inner wall. Helical flow within the ascending aorta and aortic arch help to reduce flow stagnation and increase oxygen transport. [4] As the blood moves into the descending aorta, rotations in the flow are less present.
Blood viscosity is a measure of the resistance of blood to flow. It can also be described as the thickness and stickiness of blood. This biophysical property makes it a critical determinant of friction against the vessel walls, the rate of venous return, the work required for the heart to pump blood, and how much oxygen is transported to tissues and organs.
A Wiggers diagram modified from [1]. A Wiggers diagram, named after its developer, Carl Wiggers, is a unique diagram that has been used in teaching cardiac physiology for more than a century.
The theory of the velocity of the transmission of the pulse through the circulation dates back to 1808 with the work of Thomas Young. [9] The relationship between pulse wave velocity (PWV) and arterial wall stiffness can be derived from Newton's second law of motion (=) applied to a small fluid element, where the force on the element equals the product of density (the mass per unit volume ...
Velocity Time Integral is a clinical Doppler ultrasound measurement of blood flow, equivalent to the area under the velocity time curve. The product of VTI (cm/stroke) and the cross sectional area of a valve (cm2) yields a stroke volume (cm3/stroke), which can be used to calculate cardiac output.
The Moens–Korteweg equation states that PWV is proportional to the square root of the incremental elastic modulus, (E inc), of the vessel wall given constant ratio of wall thickness, h, to vessel radius, r, and blood density, ρ, assuming that the artery wall is isotropic and experiences isovolumetric change with pulse pressure.
Below are several examples of differing types of local blood flow regulation by specific organ type or organ system. In each case, there is a specific type of intrinsic regulation occurring in order to maintain or alter blood flow to that given organ alone, instead of creating a systemic change that would affect the entire body.