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Top Prescription Weight Loss Pills. Anti-obesity medications (AOMs) date back to the 1940s — well before modern regulations from the FDA (U.S. Food and Drug Administration) (FDA) were in place ...
Originally available only by prescription, it was approved by the FDA for over-the-counter sale in February 2007. [32] In May 2010, the U.S. Food and Drug Administration (FDA) approved a revised label for Xenical to include new safety information about rare cases of severe liver injury that have been reported with the use of this medication. [33]
That said, the Food and Drug Administration has approved certain weight loss pills for short-term vs. long-term use. As mentioned above, phentermine is only FDA-approved for short-term use (up to ...
Amfepramone, also known as diethylpropion, is a stimulant drug of the phenethylamine, amphetamine, and cathinone classes that is used as an appetite suppressant. [ 8 ] [ 9 ] It is used in the short-term management of obesity , along with dietary and lifestyle changes. [ 8 ]
Having paid a fee under the Prescription Drug User Fee Act, Orexigen was given a deadline for the FDA to approve or reject the drug of January 2011. In December 2010, an FDA Advisory Committee voted 13-7 for the approval of Contrave and voted 11-8 for the conduct of a post-marketing cardiovascular outcomes study. [ 18 ]
These medications belong to a class of drugs called GLP-1 agonists. They work by increasing feelings of fullness, slowing down the process of stomach emptying, and reducing appetite.
Orlistat, sold under the brand name Xenical among others, is a medication used to treat obesity. Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet. [4]
Phentermine is more potent in its effects on norepinephrine than on dopamine and the drug shows only weak effects on serotonin. [ 8 ] [ 9 ] [ 10 ] Unlike many other amphetamines and MRAs, phentermine is completely inactive at the vesicular monoamine transporter 2 (VMAT2).
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