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Carbon monoxide poisoningtypically occurs from breathingin carbon monoxide(CO) at excessive levels.[3] Symptoms are often described as "flu-like" and commonly include headache, dizziness, weakness, vomiting, chest pain, and confusion.[1] Large exposures can result in loss of consciousness, arrhythmias, seizures, or death.
Dopamine (DA, a contraction of 3,4- d ihydr o xy p henethyl amine) is a neuromodulatory molecule that plays several important roles in cells. It is an organic chemical of the catecholamine and phenethylamine families. Dopamine constitutes about 80% of the catecholamine content in the brain.
See also: Neurotransmission. Synthesis. [edit] Neurotransmitters are generally synthesized in neurons and are made up of, or derived from, precursor molecules that are found abundantly in the cell. Classes of neurotransmitters include amino acids, monoamines, and peptides. Monoamines are synthesized by altering a single amino acid.
Chemoreceptor trigger zone. The chemoreceptor trigger zone (CTZ) is an area of the medulla oblongata that receives inputs from blood -borne drugs or hormones, and communicates with other structures in the vomiting center to initiate vomiting. The CTZ is located within the area postrema, which is on the floor of the fourth ventricle and is ...
Carbogen. Carbogen, also called Meduna's Mixture after its inventor Ladislas Meduna, is a mixture of carbon dioxide and oxygen gas. Meduna's original formula was 30% CO 2 and 70% oxygen, but the term carbogen can refer to any mixture of these two gases, from 1.5% [1] to 50% [2] CO 2.
3,4-Methylenedioxyamphetamine (MDA), sometimes referred to as “sass,” is an empathogen-entactogen, stimulant, and psychedelic drug of the amphetamine family that is encountered mainly as a recreational drug. In its pharmacology, MDA is a serotonin–norepinephrine–dopamine releasing agent (SNDRA). In most countries, the drug is a ...
The enzyme acetaldehyde dehydrogenase (aldehyde dehydrogenase 2 family ALDH2, EC 1.2.1.3) then converts the acetaldehyde into the non-toxic acetate ion (commonly found in acetic acid or vinegar). [ 71 ] [ 93 ] This ion is in turn is broken down into carbon dioxide and water . [ 71 ]
Once the drug cannot pass back through the barrier the drug can be concentrated and made effective for therapeutic use. [7] However drawbacks to this exist as well. Once the drug is in the brain there is a point where it needs to be degraded to prevent overdose to the brain tissue. Also if the drug cannot pass back through the blood–brain ...